LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A NU7441
3.33
uM
LJP5
 3
C08
 72
hr
 962 8307 10315 0.8053 0.8774
MCF 10A NU7441
10
uM
LJP5
 1
C07
 72
hr
 962 2231 10714 0.2082 0.2736
MCF 10A NU7441
10
uM
LJP5
 2
C07
 72
hr
 962 1741 10507 0.1657 0.1876
MCF 10A NU7441
10
uM
LJP5
 3
C07
 72
hr
 962 1529 10315 0.1482 0.1449
MCF 10A OSI-027
0.04
uM
LJP6
 1
E12
 72
hr
 962 7092 10693 0.6632 0.7770
MCF 10A OSI-027
0.04
uM
LJP6
 2
E12
 72
hr
 962 7184 10740 0.6689 0.7818
MCF 10A OSI-027
0.04
uM
LJP6
 3
E12
 72
hr
 962 8088 10641 0.7600 0.8478
MCF 10A OSI-027
0.12
uM
LJP6
 1
E11
 72
hr
 962 4653 10693 0.4351 0.5740
MCF 10A OSI-027
0.12
uM
LJP6
 2
E11
 72
hr
 962 4412 10740 0.4108 0.5489
MCF 10A OSI-027
0.12
uM
LJP6
 3
E11
 72
hr
 962 4944 10641 0.4646 0.6033
MCF 10A OSI-027
0.37
uM
LJP6
 1
E10
 72
hr
 962 2785 10693 0.2604 0.3579
MCF 10A OSI-027
0.37
uM
LJP6
 2
E10
 72
hr
 962 2482 10740 0.2311 0.3129
MCF 10A OSI-027
0.37
uM
LJP6
 3
E10
 72
hr
 962 2927 10641 0.2751 0.3783
MCF 10A OSI-027
1.11
uM
LJP6
 1
E09
 72
hr
 962 1985 10693 0.1856 0.2318
MCF 10A OSI-027
1.11
uM
LJP6
 2
E09
 72
hr
 962 2212 10740 0.2059 0.2702
MCF 10A OSI-027
1.11
uM
LJP6
 3
E09
 72
hr
 962 2346 10641 0.2205 0.2931
MCF 10A OSI-027
3.33
uM
LJP6
 1
E08
 72
hr
 962 1721 10693 0.1609 0.1822
MCF 10A OSI-027
3.33
uM
LJP6
 2
E08
 72
hr
 962 1533 10740 0.1427 0.1432
MCF 10A OSI-027
3.33
uM
LJP6
 3
E08
 72
hr
 962 1472 10641 0.1383 0.1305
MCF 10A OSI-027
10
uM
LJP6
 1
E07
 72
hr
 962 1612 10693 0.1507 0.1601
MCF 10A OSI-027
10
uM
LJP6
 2
E07
 72
hr
 962 1372 10740 0.1277 0.1073
MCF 10A OSI-027
10
uM
LJP6
 3
E07
 72
hr
 962 1558 10641 0.1464 0.1491
MCF 10A WYE-125132
0.04
uM
LJP6
 1
L12
 72
hr
 962 3085 10693 0.2885 0.3984
MCF 10A WYE-125132
0.04
uM
LJP6
 2
L12
 72
hr
 962 2854 10740 0.2657 0.3667
MCF 10A WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 962 3320 10641 0.3120 0.4293