LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A R406
10
uM
LJP6
 2
C13
 72
hr
 962 5011 10740 0.4665 0.6066
MCF 10A R406
10
uM
LJP6
 3
C13
 72
hr
 962 6011 10641 0.5649 0.6962
MCF 10A BI-2536
0.04
uM
LJP6
 1
D18
 72
hr
 962 711 10693 0.0665 -0.0834
MCF 10A BI-2536
0.04
uM
LJP6
 2
D18
 72
hr
 962 846 10740 0.0788 -0.0363
MCF 10A BI-2536
0.04
uM
LJP6
 3
D18
 72
hr
 962 801 10641 0.0753 -0.0515
MCF 10A BI-2536
0.12
uM
LJP6
 1
D17
 72
hr
 962 927 10693 0.0867 -0.0107
MCF 10A BI-2536
0.12
uM
LJP6
 2
D17
 72
hr
 962 864 10740 0.0804 -0.0304
MCF 10A BI-2536
0.12
uM
LJP6
 3
D17
 72
hr
 962 903 10641 0.0849 -0.0181
MCF 10A BI-2536
0.37
uM
LJP6
 1
D16
 72
hr
 962 953 10693 0.0891 -0.0027
MCF 10A BI-2536
0.37
uM
LJP6
 2
D16
 72
hr
 962 992 10740 0.0924 0.0088
MCF 10A BI-2536
0.37
uM
LJP6
 3
D16
 72
hr
 962 1055 10641 0.0991 0.0269
MCF 10A BI-2536
1.11
uM
LJP6
 1
D15
 72
hr
 962 926 10693 0.0866 -0.0110
MCF 10A BI-2536
1.11
uM
LJP6
 2
D15
 72
hr
 962 940 10740 0.0875 -0.0067
MCF 10A BI-2536
1.11
uM
LJP6
 3
D15
 72
hr
 962 1024 10641 0.0962 0.0181
MCF 10A BI-2536
3.33
uM
LJP6
 1
D14
 72
hr
 962 870 10693 0.0814 -0.0286
MCF 10A BI-2536
3.33
uM
LJP6
 2
D14
 72
hr
 962 882 10740 0.0821 -0.0247
MCF 10A BI-2536
3.33
uM
LJP6
 3
D14
 72
hr
 962 964 10641 0.0906 0.0006
MCF 10A BI-2536
10
uM
LJP6
 1
D13
 72
hr
 962 817 10693 0.0764 -0.0460
MCF 10A BI-2536
10
uM
LJP6
 2
D13
 72
hr
 962 875 10740 0.0815 -0.0269
MCF 10A BI-2536
10
uM
LJP6
 3
D13
 72
hr
 962 1037 10641 0.0974 0.0218
MCF 10A A443654
0.04
uM
LJP6
 1
I24
 72
hr
 962 10929 10693 1.0220 1.0126
MCF 10A A443654
0.04
uM
LJP6
 2
I24
 72
hr
 962 11126 10740 1.0359 1.0203
MCF 10A A443654
0.04
uM
LJP6
 3
I24
 72
hr
 962 10731 10641 1.0084 1.0048
MCF 10A A443654
0.12
uM
LJP6
 1
I23
 72
hr
 962 7869 10693 0.7359 0.8310
MCF 10A A443654
0.12
uM
LJP6
 2
I23
 72
hr
 962 7491 10740 0.6974 0.8033