LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A SB590885
3.33
uM
LJP5
 1
L14
 72
hr
 962 10022 10714 0.9354 0.9620
MCF 10A SB590885
3.33
uM
LJP5
 2
L14
 72
hr
 962 9876 10507 0.9399 0.9644
MCF 10A SB590885
3.33
uM
LJP5
 3
L14
 72
hr
 962 9498 10315 0.9208 0.9523
MCF 10A SB590885
10
uM
LJP5
 1
L13
 72
hr
 962 6287 10714 0.5868 0.7157
MCF 10A SB590885
10
uM
LJP5
 2
L13
 72
hr
 962 6273 10507 0.5970 0.7222
MCF 10A SB590885
10
uM
LJP5
 3
L13
 72
hr
 962 5851 10315 0.5672 0.6946
MCF 10A Pictilisib
0.04
uM
LJP6
 1
D24
 72
hr
 962 10248 10693 0.9583 0.9757
MCF 10A Pictilisib
0.04
uM
LJP6
 2
D24
 72
hr
 962 10856 10740 1.0107 1.0061
MCF 10A Pictilisib
0.04
uM
LJP6
 3
D24
 72
hr
 962 10843 10641 1.0189 1.0108
MCF 10A Pictilisib
0.12
uM
LJP6
 1
D23
 72
hr
 962 9293 10693 0.8690 0.9208
MCF 10A Pictilisib
0.12
uM
LJP6
 2
D23
 72
hr
 962 9148 10740 0.8517 0.9099
MCF 10A Pictilisib
0.12
uM
LJP6
 3
D23
 72
hr
 962 9870 10641 0.9275 0.9571
MCF 10A Pictilisib
0.37
uM
LJP6
 1
D22
 72
hr
 962 7085 10693 0.6625 0.7765
MCF 10A Pictilisib
0.37
uM
LJP6
 2
D22
 72
hr
 962 6947 10740 0.6468 0.7647
MCF 10A Pictilisib
0.37
uM
LJP6
 3
D22
 72
hr
 962 7084 10641 0.6657 0.7785
MCF 10A Pictilisib
1.11
uM
LJP6
 1
D21
 72
hr
 962 4219 10693 0.3945 0.5303
MCF 10A Pictilisib
1.11
uM
LJP6
 2
D21
 72
hr
 962 3989 10740 0.3714 0.5047
MCF 10A Pictilisib
1.11
uM
LJP6
 3
D21
 72
hr
 962 4106 10641 0.3858 0.5197
MCF 10A Pictilisib
3.33
uM
LJP6
 1
D20
 72
hr
 962 2570 10693 0.2403 0.3268
MCF 10A Pictilisib
3.33
uM
LJP6
 2
D20
 72
hr
 962 2753 10740 0.2563 0.3526
MCF 10A Pictilisib
3.33
uM
LJP6
 3
D20
 72
hr
 962 3024 10641 0.2842 0.3914
MCF 10A Pictilisib
10
uM
LJP6
 1
D19
 72
hr
 962 1258 10693 0.1176 0.0802
MCF 10A Pictilisib
10
uM
LJP6
 2
D19
 72
hr
 962 1266 10740 0.1179 0.0820
MCF 10A Pictilisib
10
uM
LJP6
 3
D19
 72
hr
 962 1334 10641 0.1254 0.0988
MCF 10A PD184352
0.04
uM
LJP5
 1
L12
 72
hr
 962 5921 10714 0.5526 0.6864