LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Imatinib
3.33
uM
LJP6
 3
N14
 72
hr
 962 10169 10641 0.9556 0.9740
MCF 10A Imatinib
10
uM
LJP6
 1
N13
 72
hr
 962 10360 10693 0.9688 0.9818
MCF 10A Imatinib
10
uM
LJP6
 2
N13
 72
hr
 962 10238 10740 0.9532 0.9726
MCF 10A Imatinib
10
uM
LJP6
 3
N13
 72
hr
 962 9516 10641 0.8942 0.9365
MCF 10A NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 962 9509 10693 0.8892 0.9335
MCF 10A NVP-TAE684
0.04
uM
LJP6
 2
K18
 72
hr
 962 9699 10740 0.9030 0.9422
MCF 10A NVP-TAE684
0.04
uM
LJP6
 3
K18
 72
hr
 962 9241 10641 0.8684 0.9202
MCF 10A NVP-TAE684
0.12
uM
LJP6
 1
K17
 72
hr
 962 8354 10693 0.7812 0.8628
MCF 10A NVP-TAE684
0.12
uM
LJP6
 2
K17
 72
hr
 962 8222 10740 0.7655 0.8522
MCF 10A NVP-TAE684
0.12
uM
LJP6
 3
K17
 72
hr
 962 7832 10641 0.7360 0.8308
MCF 10A NVP-TAE684
0.37
uM
LJP6
 1
K16
 72
hr
 962 7281 10693 0.6809 0.7905
MCF 10A NVP-TAE684
0.37
uM
LJP6
 2
K16
 72
hr
 962 7089 10740 0.6600 0.7750
MCF 10A NVP-TAE684
0.37
uM
LJP6
 3
K16
 72
hr
 962 6700 10641 0.6296 0.7502
MCF 10A NVP-TAE684
1.11
uM
LJP6
 1
K15
 72
hr
 962 6294 10693 0.5886 0.7170
MCF 10A NVP-TAE684
1.11
uM
LJP6
 2
K15
 72
hr
 962 5711 10740 0.5317 0.6681
MCF 10A NVP-TAE684
1.11
uM
LJP6
 3
K15
 72
hr
 962 4368 10641 0.4105 0.5470
MCF 10A NVP-TAE684
3.33
uM
LJP6
 1
K14
 72
hr
 962 5127 10693 0.4794 0.6186
MCF 10A NVP-TAE684
3.33
uM
LJP6
 2
K14
 72
hr
 962 4595 10740 0.4278 0.5671
MCF 10A NVP-TAE684
3.33
uM
LJP6
 3
K14
 72
hr
 962 3654 10641 0.3434 0.4694
MCF 10A NVP-TAE684
10
uM
LJP6
 1
K13
 72
hr
 962 995 10693 0.0930 0.0097
MCF 10A NVP-TAE684
10
uM
LJP6
 2
K13
 72
hr
 962 1065 10740 0.0992 0.0296
MCF 10A NVP-TAE684
10
uM
LJP6
 3
K13
 72
hr
 962 1009 10641 0.0948 0.0138
MCF 10A CGP60474
0.04
uM
LJP6
 1
G06
 72
hr
 962 356 10693 0.0333 -0.2489
MCF 10A CGP60474
0.04
uM
LJP6
 2
G06
 72
hr
 962 413 10740 0.0385 -0.2157
MCF 10A CGP60474
0.04
uM
LJP6
 3
G06
 72
hr
 962 433 10641 0.0407 -0.2057