LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A AZD8055
10
uM
LJP6
 2
A07
 72
hr
 962 50 10740 0.0047 -0.5724
MCF 10A AZD8055
10
uM
LJP6
 3
A07
 72
hr
 962 57 10641 0.0054 -0.5574
MCF 10A Sorafenib
0.04
uM
LJP6
 1
B12
 72
hr
 962 9860 10693 0.9220 0.9538
MCF 10A Sorafenib
0.04
uM
LJP6
 2
B12
 72
hr
 962 10008 10740 0.9318 0.9598
MCF 10A Sorafenib
0.04
uM
LJP6
 3
B12
 72
hr
 962 10633 10641 0.9992 0.9995
MCF 10A Sorafenib
0.12
uM
LJP6
 1
B11
 72
hr
 962 9352 10693 0.8745 0.9243
MCF 10A Sorafenib
0.12
uM
LJP6
 2
B11
 72
hr
 962 9335 10740 0.8691 0.9210
MCF 10A Sorafenib
0.12
uM
LJP6
 3
B11
 72
hr
 962 10308 10641 0.9687 0.9817
MCF 10A Sorafenib
0.37
uM
LJP6
 1
B10
 72
hr
 962 9227 10693 0.8629 0.9169
MCF 10A Sorafenib
0.37
uM
LJP6
 2
B10
 72
hr
 962 9103 10740 0.8475 0.9072
MCF 10A Sorafenib
0.37
uM
LJP6
 3
B10
 72
hr
 962 9778 10641 0.9188 0.9518
MCF 10A Sorafenib
1.11
uM
LJP6
 1
B09
 72
hr
 962 9263 10693 0.8662 0.9190
MCF 10A Sorafenib
1.11
uM
LJP6
 2
B09
 72
hr
 962 9274 10740 0.8634 0.9174
MCF 10A Sorafenib
1.11
uM
LJP6
 3
B09
 72
hr
 962 9866 10641 0.9271 0.9568
MCF 10A Sorafenib
3.33
uM
LJP6
 1
B08
 72
hr
 962 8784 10693 0.8214 0.8899
MCF 10A Sorafenib
3.33
uM
LJP6
 2
B08
 72
hr
 962 9239 10740 0.8602 0.9153
MCF 10A Sorafenib
3.33
uM
LJP6
 3
B08
 72
hr
 962 9340 10641 0.8777 0.9261
MCF 10A Sorafenib
10
uM
LJP6
 1
B07
 72
hr
 962 4395 10693 0.4110 0.5484
MCF 10A Sorafenib
10
uM
LJP6
 2
B07
 72
hr
 962 4047 10740 0.3768 0.5109
MCF 10A Sorafenib
10
uM
LJP6
 3
B07
 72
hr
 962 4801 10641 0.4512 0.5898
MCF 10A CP466722
0.04
uM
LJP5
 1
I12
 72
hr
 962 10975 10714 1.0244 1.0139
MCF 10A CP466722
0.04
uM
LJP5
 2
I12
 72
hr
 962 10592 10507 1.0080 1.0046
MCF 10A CP466722
0.04
uM
LJP5
 3
I12
 72
hr
 962 10313 10315 0.9998 0.9999
MCF 10A CP466722
0.12
uM
LJP5
 1
I11
 72
hr
 962 10658 10714 0.9948 0.9970
MCF 10A CP466722
0.12
uM
LJP5
 2
I11
 72
hr
 962 10405 10507 0.9902 0.9943