LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Tozasertib
0.37
uM
LJP5
 2
B16
 72
hr
 962 1327 10507 0.1263 0.0977
MCF 10A Tozasertib
0.37
uM
LJP5
 3
B16
 72
hr
 962 1339 10315 0.1298 0.1014
MCF 10A Tozasertib
1.11
uM
LJP5
 1
B15
 72
hr
 962 1441 10714 0.1345 0.1232
MCF 10A Tozasertib
1.11
uM
LJP5
 2
B15
 72
hr
 962 1234 10507 0.1174 0.0748
MCF 10A Tozasertib
1.11
uM
LJP5
 3
B15
 72
hr
 962 1493 10315 0.1447 0.1370
MCF 10A Tozasertib
3.33
uM
LJP5
 1
B14
 72
hr
 962 1385 10714 0.1293 0.1105
MCF 10A Tozasertib
3.33
uM
LJP5
 2
B14
 72
hr
 962 1242 10507 0.1182 0.0768
MCF 10A Tozasertib
3.33
uM
LJP5
 3
B14
 72
hr
 962 1419 10315 0.1376 0.1202
MCF 10A Tozasertib
10
uM
LJP5
 1
B13
 72
hr
 962 1309 10714 0.1222 0.0926
MCF 10A Tozasertib
10
uM
LJP5
 2
B13
 72
hr
 962 1197 10507 0.1139 0.0654
MCF 10A Tozasertib
10
uM
LJP5
 3
B13
 72
hr
 962 1294 10315 0.1255 0.0904
MCF 10A Imatinib
0.04
uM
LJP6
 1
N18
 72
hr
 962 10847 10693 1.0143 1.0082
MCF 10A Imatinib
0.04
uM
LJP6
 2
N18
 72
hr
 962 10611 10740 0.9879 0.9930
MCF 10A Imatinib
0.04
uM
LJP6
 3
N18
 72
hr
 962 10683 10641 1.0039 1.0022
MCF 10A Imatinib
0.12
uM
LJP6
 1
N17
 72
hr
 962 10665 10693 0.9973 0.9985
MCF 10A Imatinib
0.12
uM
LJP6
 2
N17
 72
hr
 962 10954 10740 1.0199 1.0113
MCF 10A Imatinib
0.12
uM
LJP6
 3
N17
 72
hr
 962 10588 10641 0.9950 0.9971
MCF 10A Imatinib
0.37
uM
LJP6
 1
N16
 72
hr
 962 10790 10693 1.0090 1.0052
MCF 10A Imatinib
0.37
uM
LJP6
 2
N16
 72
hr
 962 10606 10740 0.9875 0.9928
MCF 10A Imatinib
0.37
uM
LJP6
 3
N16
 72
hr
 962 10490 10641 0.9858 0.9917
MCF 10A Imatinib
1.11
uM
LJP6
 1
N15
 72
hr
 962 10766 10693 1.0068 1.0039
MCF 10A Imatinib
1.11
uM
LJP6
 2
N15
 72
hr
 962 10564 10740 0.9835 0.9905
MCF 10A Imatinib
1.11
uM
LJP6
 3
N15
 72
hr
 962 10251 10641 0.9633 0.9785
MCF 10A Imatinib
3.33
uM
LJP6
 1
N14
 72
hr
 962 10787 10693 1.0087 1.0050
MCF 10A Imatinib
3.33
uM
LJP6
 2
N14
 72
hr
 962 10839 10740 1.0091 1.0052