LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Dasatinib
1.11
uM
LJP6
 1
I03
 72
hr
 962 1165 10693 0.1089 0.0566
MCF 10A Dasatinib
1.11
uM
LJP6
 2
I03
 72
hr
 962 1219 10740 0.1135 0.0703
MCF 10A Dasatinib
1.11
uM
LJP6
 3
I03
 72
hr
 962 1433 10641 0.1347 0.1218
MCF 10A Dasatinib
1.11
uM
LJP5
 1
D03
 72
hr
 962 1829 10714 0.1707 0.2029
MCF 10A Dasatinib
1.11
uM
LJP5
 2
D03
 72
hr
 962 1904 10507 0.1812 0.2188
MCF 10A Dasatinib
1.11
uM
LJP5
 3
D03
 72
hr
 962 2037 10315 0.1975 0.2450
MCF 10A Dasatinib
3.33
uM
LJP6
 1
I02
 72
hr
 962 904 10693 0.0845 -0.0178
MCF 10A Dasatinib
3.33
uM
LJP6
 2
I02
 72
hr
 962 893 10740 0.0831 -0.0212
MCF 10A Dasatinib
3.33
uM
LJP6
 3
I02
 72
hr
 962 1114 10641 0.1047 0.0432
MCF 10A Dasatinib
3.33
uM
LJP5
 1
D02
 72
hr
 962 1213 10714 0.1132 0.0689
MCF 10A Dasatinib
3.33
uM
LJP5
 2
D02
 72
hr
 962 1097 10507 0.1044 0.0388
MCF 10A Dasatinib
3.33
uM
LJP5
 3
D02
 72
hr
 962 1519 10315 0.1473 0.1427
MCF 10A Dasatinib
10
uM
LJP6
 1
I01
 72
hr
 962 602 10693 0.0563 -0.1263
MCF 10A Dasatinib
10
uM
LJP6
 2
I01
 72
hr
 962 451 10740 0.0420 -0.1956
MCF 10A Dasatinib
10
uM
LJP6
 3
I01
 72
hr
 962 490 10641 0.0460 -0.1769
MCF 10A Dasatinib
10
uM
LJP5
 1
D01
 72
hr
 962 736 10714 0.0687 -0.0742
MCF 10A Dasatinib
10
uM
LJP5
 2
D01
 72
hr
 962 847 10507 0.0806 -0.0363
MCF 10A Dasatinib
10
uM
LJP5
 3
D01
 72
hr
 962 763 10315 0.0740 -0.0655
MCF 10A Tozasertib
0.04
uM
LJP5
 1
B18
 72
hr
 962 2028 10714 0.1893 0.2392
MCF 10A Tozasertib
0.04
uM
LJP5
 2
B18
 72
hr
 962 2026 10507 0.1928 0.2410
MCF 10A Tozasertib
0.04
uM
LJP5
 3
B18
 72
hr
 962 2157 10315 0.2091 0.2660
MCF 10A Tozasertib
0.12
uM
LJP5
 1
B17
 72
hr
 962 1504 10714 0.1404 0.1371
MCF 10A Tozasertib
0.12
uM
LJP5
 2
B17
 72
hr
 962 1485 10507 0.1413 0.1341
MCF 10A Tozasertib
0.12
uM
LJP5
 3
B17
 72
hr
 962 1471 10315 0.1426 0.1321
MCF 10A Tozasertib
0.37
uM
LJP5
 1
B16
 72
hr
 962 1486 10714 0.1387 0.1332