LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A JW-7-24-1
1.11
uM
LJP6
 3
B21
 72
hr
 962 8963 10641 0.8423 0.9034
MCF 10A JW-7-24-1
3.33
uM
LJP6
 1
B20
 72
hr
 962 6623 10693 0.6193 0.7424
MCF 10A JW-7-24-1
3.33
uM
LJP6
 2
B20
 72
hr
 962 6878 10740 0.6404 0.7596
MCF 10A JW-7-24-1
3.33
uM
LJP6
 3
B20
 72
hr
 962 7200 10641 0.6766 0.7869
MCF 10A JW-7-24-1
10
uM
LJP6
 1
B19
 72
hr
 962 1510 10693 0.1412 0.1385
MCF 10A JW-7-24-1
10
uM
LJP6
 2
B19
 72
hr
 962 1309 10740 0.1219 0.0925
MCF 10A JW-7-24-1
10
uM
LJP6
 3
B19
 72
hr
 962 1561 10641 0.1467 0.1498
MCF 10A Dasatinib
0.04
uM
LJP6
 1
I06
 72
hr
 962 2946 10693 0.2755 0.3800
MCF 10A Dasatinib
0.04
uM
LJP6
 2
I06
 72
hr
 962 3062 10740 0.2851 0.3946
MCF 10A Dasatinib
0.04
uM
LJP6
 3
I06
 72
hr
 962 2649 10641 0.2489 0.3392
MCF 10A Dasatinib
0.04
uM
LJP5
 1
D06
 72
hr
 962 9444 10714 0.8815 0.9287
MCF 10A Dasatinib
0.04
uM
LJP5
 2
D06
 72
hr
 962 9020 10507 0.8584 0.9134
MCF 10A Dasatinib
0.04
uM
LJP5
 3
D06
 72
hr
 962 8395 10315 0.8139 0.8832
MCF 10A Dasatinib
0.12
uM
LJP6
 1
I05
 72
hr
 962 2279 10693 0.2131 0.2817
MCF 10A Dasatinib
0.12
uM
LJP6
 2
I05
 72
hr
 962 2329 10740 0.2168 0.2891
MCF 10A Dasatinib
0.12
uM
LJP6
 3
I05
 72
hr
 962 2342 10641 0.2201 0.2925
MCF 10A Dasatinib
0.12
uM
LJP5
 1
D05
 72
hr
 962 6464 10714 0.6033 0.7295
MCF 10A Dasatinib
0.12
uM
LJP5
 2
D05
 72
hr
 962 5799 10507 0.5519 0.6834
MCF 10A Dasatinib
0.12
uM
LJP5
 3
D05
 72
hr
 962 6229 10315 0.6039 0.7259
MCF 10A Dasatinib
0.37
uM
LJP6
 1
I04
 72
hr
 962 2003 10693 0.1873 0.2350
MCF 10A Dasatinib
0.37
uM
LJP6
 2
I04
 72
hr
 962 1986 10740 0.1849 0.2315
MCF 10A Dasatinib
0.37
uM
LJP6
 3
I04
 72
hr
 962 2047 10641 0.1924 0.2433
MCF 10A Dasatinib
0.37
uM
LJP5
 1
D04
 72
hr
 962 3063 10714 0.2859 0.3952
MCF 10A Dasatinib
0.37
uM
LJP5
 2
D04
 72
hr
 962 3155 10507 0.3003 0.4110
MCF 10A Dasatinib
0.37
uM
LJP5
 3
D04
 72
hr
 962 3042 10315 0.2949 0.3998