LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Neratinib
0.12
uM
LJP5
 2
A17
 72
hr
 962 3129 10507 0.2978 0.4076
MCF 10A Neratinib
0.12
uM
LJP5
 3
A17
 72
hr
 962 3411 10315 0.3307 0.4474
MCF 10A Neratinib
0.37
uM
LJP5
 1
A16
 72
hr
 962 1691 10714 0.1578 0.1761
MCF 10A Neratinib
0.37
uM
LJP5
 2
A16
 72
hr
 962 1678 10507 0.1597 0.1750
MCF 10A Neratinib
0.37
uM
LJP5
 3
A16
 72
hr
 962 1440 10315 0.1396 0.1250
MCF 10A Neratinib
1.11
uM
LJP5
 1
A15
 72
hr
 962 1511 10714 0.1410 0.1386
MCF 10A Neratinib
1.11
uM
LJP5
 2
A15
 72
hr
 962 1733 10507 0.1649 0.1860
MCF 10A Neratinib
1.11
uM
LJP5
 3
A15
 72
hr
 962 1546 10315 0.1499 0.1486
MCF 10A Neratinib
3.33
uM
LJP5
 1
A14
 72
hr
 962 1428 10714 0.1333 0.1203
MCF 10A Neratinib
3.33
uM
LJP5
 2
A14
 72
hr
 962 1601 10507 0.1524 0.1591
MCF 10A Neratinib
3.33
uM
LJP5
 3
A14
 72
hr
 962 1523 10315 0.1477 0.1436
MCF 10A Neratinib
10
uM
LJP5
 1
A13
 72
hr
 962 1746 10714 0.1630 0.1869
MCF 10A Neratinib
10
uM
LJP5
 2
A13
 72
hr
 962 1409 10507 0.1341 0.1169
MCF 10A Neratinib
10
uM
LJP5
 3
A13
 72
hr
 962 1665 10315 0.1614 0.1738
MCF 10A JW-7-24-1
0.04
uM
LJP6
 1
B24
 72
hr
 962 11039 10693 1.0323 1.0184
MCF 10A JW-7-24-1
0.04
uM
LJP6
 2
B24
 72
hr
 962 10798 10740 1.0053 1.0031
MCF 10A JW-7-24-1
0.04
uM
LJP6
 3
B24
 72
hr
 962 10955 10641 1.0294 1.0168
MCF 10A JW-7-24-1
0.12
uM
LJP6
 1
B23
 72
hr
 962 10511 10693 0.9829 0.9901
MCF 10A JW-7-24-1
0.12
uM
LJP6
 2
B23
 72
hr
 962 10604 10740 0.9873 0.9927
MCF 10A JW-7-24-1
0.12
uM
LJP6
 3
B23
 72
hr
 962 10417 10641 0.9789 0.9877
MCF 10A JW-7-24-1
0.37
uM
LJP6
 1
B22
 72
hr
 962 9656 10693 0.9030 0.9421
MCF 10A JW-7-24-1
0.37
uM
LJP6
 2
B22
 72
hr
 962 9647 10740 0.8982 0.9392
MCF 10A JW-7-24-1
0.37
uM
LJP6
 3
B22
 72
hr
 962 10059 10641 0.9453 0.9678
MCF 10A JW-7-24-1
1.11
uM
LJP6
 1
B21
 72
hr
 962 8850 10693 0.8276 0.8940
MCF 10A JW-7-24-1
1.11
uM
LJP6
 2
B21
 72
hr
 962 8321 10740 0.7747 0.8586