LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A HG-5-88-01
10
uM
LJP6
 1
A19
 72
hr
 962 3599 10693 0.3366 0.4619
MCF 10A HG-5-88-01
10
uM
LJP6
 2
A19
 72
hr
 962 3726 10740 0.3469 0.4755
MCF 10A HG-5-88-01
10
uM
LJP6
 3
A19
 72
hr
 962 3993 10641 0.3752 0.5075
MCF 10A HG-6-64-01
0.04
uM
LJP6
 1
M06
 72
hr
 962 10248 10693 0.9583 0.9757
MCF 10A HG-6-64-01
0.04
uM
LJP6
 2
M06
 72
hr
 962 10211 10740 0.9507 0.9712
MCF 10A HG-6-64-01
0.04
uM
LJP6
 3
M06
 72
hr
 962 9775 10641 0.9186 0.9516
MCF 10A HG-6-64-01
0.12
uM
LJP6
 1
M05
 72
hr
 962 10165 10693 0.9506 0.9710
MCF 10A HG-6-64-01
0.12
uM
LJP6
 2
M05
 72
hr
 962 10175 10740 0.9473 0.9692
MCF 10A HG-6-64-01
0.12
uM
LJP6
 3
M05
 72
hr
 962 9826 10641 0.9234 0.9545
MCF 10A HG-6-64-01
0.37
uM
LJP6
 1
M04
 72
hr
 962 10157 10693 0.9498 0.9706
MCF 10A HG-6-64-01
0.37
uM
LJP6
 2
M04
 72
hr
 962 10564 10740 0.9835 0.9905
MCF 10A HG-6-64-01
0.37
uM
LJP6
 3
M04
 72
hr
 962 10306 10641 0.9685 0.9816
MCF 10A HG-6-64-01
1.11
uM
LJP6
 1
M03
 72
hr
 962 9121 10693 0.8529 0.9105
MCF 10A HG-6-64-01
1.11
uM
LJP6
 2
M03
 72
hr
 962 9378 10740 0.8731 0.9235
MCF 10A HG-6-64-01
1.11
uM
LJP6
 3
M03
 72
hr
 962 9090 10641 0.8542 0.9111
MCF 10A HG-6-64-01
3.33
uM
LJP6
 1
M02
 72
hr
 962 6264 10693 0.5858 0.7147
MCF 10A HG-6-64-01
3.33
uM
LJP6
 2
M02
 72
hr
 962 6511 10740 0.6062 0.7321
MCF 10A HG-6-64-01
3.33
uM
LJP6
 3
M02
 72
hr
 962 5691 10641 0.5348 0.6697
MCF 10A HG-6-64-01
10
uM
LJP6
 1
M01
 72
hr
 962 843 10693 0.0788 -0.0373
MCF 10A HG-6-64-01
10
uM
LJP6
 2
M01
 72
hr
 962 765 10740 0.0712 -0.0638
MCF 10A HG-6-64-01
10
uM
LJP6
 3
M01
 72
hr
 962 866 10641 0.0814 -0.0299
MCF 10A Neratinib
0.04
uM
LJP5
 1
A18
 72
hr
 962 5378 10714 0.5020 0.6404
MCF 10A Neratinib
0.04
uM
LJP5
 2
A18
 72
hr
 962 4350 10507 0.4140 0.5487
MCF 10A Neratinib
0.04
uM
LJP5
 3
A18
 72
hr
 962 4891 10315 0.4742 0.6082
MCF 10A Neratinib
0.12
uM
LJP5
 1
A17
 72
hr
 962 3267 10714 0.3049 0.4213