LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T
uM
LJP5
 3
N20
 72
hr
 658 3788 3938 0.9618 0.9701
Hs 578T
uM
LJP5
 3
N21
 72
hr
 658 3918 3938 0.9948 0.9960
Hs 578T
uM
LJP5
 3
N22
 72
hr
 658 3782 3938 0.9603 0.9688
Hs 578T
uM
LJP5
 3
N23
 72
hr
 658 3946 3938 1.0019 1.0015
Hs 578T
uM
LJP5
 3
N24
 72
hr
 658 3713 3938 0.9428 0.9548
MCF 10A Seliciclib
0.04
uM
LJP5
 1
J06
 72
hr
 962 10392 10714 0.9700 0.9825
MCF 10A Seliciclib
0.04
uM
LJP5
 2
J06
 72
hr
 962 10414 10507 0.9911 0.9948
MCF 10A Seliciclib
0.04
uM
LJP5
 3
J06
 72
hr
 962 10002 10315 0.9696 0.9821
MCF 10A Seliciclib
0.12
uM
LJP5
 1
J05
 72
hr
 962 10054 10714 0.9384 0.9638
MCF 10A Seliciclib
0.12
uM
LJP5
 2
J05
 72
hr
 962 10447 10507 0.9942 0.9966
MCF 10A Seliciclib
0.12
uM
LJP5
 3
J05
 72
hr
 962 9609 10315 0.9315 0.9590
MCF 10A Seliciclib
0.37
uM
LJP5
 1
J04
 72
hr
 962 9737 10714 0.9088 0.9458
MCF 10A Seliciclib
0.37
uM
LJP5
 2
J04
 72
hr
 962 9721 10507 0.9251 0.9554
MCF 10A Seliciclib
0.37
uM
LJP5
 3
J04
 72
hr
 962 9556 10315 0.9264 0.9558
MCF 10A Seliciclib
1.11
uM
LJP5
 1
J03
 72
hr
 962 9310 10714 0.8690 0.9208
MCF 10A Seliciclib
1.11
uM
LJP5
 2
J03
 72
hr
 962 9761 10507 0.9289 0.9577
MCF 10A Seliciclib
1.11
uM
LJP5
 3
J03
 72
hr
 962 9284 10315 0.9000 0.9394
MCF 10A Seliciclib
3.33
uM
LJP5
 1
J02
 72
hr
 962 9024 10714 0.8423 0.9037
MCF 10A Seliciclib
3.33
uM
LJP5
 2
J02
 72
hr
 962 9219 10507 0.8773 0.9255
MCF 10A Seliciclib
3.33
uM
LJP5
 3
J02
 72
hr
 962 8568 10315 0.8306 0.8944
MCF 10A Seliciclib
10
uM
LJP5
 1
J01
 72
hr
 962 4511 10714 0.4210 0.5595
MCF 10A Seliciclib
10
uM
LJP5
 2
J01
 72
hr
 962 5052 10507 0.4808 0.6174
MCF 10A Seliciclib
10
uM
LJP5
 3
J01
 72
hr
 962 5012 10315 0.4859 0.6197
MCF 10A AT-7519
0.04
uM
LJP6
 1
K06
 72
hr
 962 9345 10693 0.8739 0.9239
MCF 10A AT-7519
0.04
uM
LJP6
 2
K06
 72
hr
 962 10085 10740 0.9389 0.9641