LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T CHIR-99021
10
uM
LJP6
 3
P13
 72
hr
 658 2521 3769 0.6688 0.7046
Hs 578T Linifanib
0.04
uM
LJP6
 1
J12
 72
hr
 658 3712 3705 1.0017 1.0013
Hs 578T Linifanib
0.04
uM
LJP6
 2
J12
 72
hr
 658 3767 3807 0.9893 0.9916
Hs 578T Linifanib
0.04
uM
LJP6
 3
J12
 72
hr
 658 3831 3769 1.0163 1.0129
Hs 578T Linifanib
0.12
uM
LJP6
 1
J11
 72
hr
 658 3757 3705 1.0138 1.0110
Hs 578T Linifanib
0.12
uM
LJP6
 2
J11
 72
hr
 658 3564 3807 0.9360 0.9485
Hs 578T Linifanib
0.12
uM
LJP6
 3
J11
 72
hr
 658 3756 3769 0.9964 0.9971
Hs 578T Linifanib
0.37
uM
LJP6
 1
J10
 72
hr
 658 3734 3705 1.0076 1.0061
Hs 578T Linifanib
0.37
uM
LJP6
 2
J10
 72
hr
 658 3844 3807 1.0096 1.0075
Hs 578T Linifanib
0.37
uM
LJP6
 3
J10
 72
hr
 658 3498 3769 0.9279 0.9415
Hs 578T Linifanib
1.11
uM
LJP6
 1
J09
 72
hr
 658 3481 3705 0.9393 0.9504
Hs 578T Linifanib
1.11
uM
LJP6
 2
J09
 72
hr
 658 3713 3807 0.9752 0.9802
Hs 578T Linifanib
1.11
uM
LJP6
 3
J09
 72
hr
 658 3865 3769 1.0253 1.0199
Hs 578T Linifanib
3.33
uM
LJP6
 1
J08
 72
hr
 658 3380 3705 0.9121 0.9275
Hs 578T Linifanib
3.33
uM
LJP6
 2
J08
 72
hr
 658 3656 3807 0.9602 0.9682
Hs 578T Linifanib
3.33
uM
LJP6
 3
J08
 72
hr
 658 3445 3769 0.9139 0.9297
Hs 578T Linifanib
10
uM
LJP6
 1
J07
 72
hr
 658 1958 3705 0.5284 0.5485
Hs 578T Linifanib
10
uM
LJP6
 2
J07
 72
hr
 658 1965 3807 0.5161 0.5402
Hs 578T Linifanib
10
uM
LJP6
 3
J07
 72
hr
 658 2200 3769 0.5836 0.6149
Hs 578T PIK-93
0.04
uM
LJP5
 1
K18
 72
hr
 658 3892 3908 0.9958 0.9967
Hs 578T PIK-93
0.04
uM
LJP5
 2
K18
 72
hr
 658 3958 3953 1.0011 1.0008
Hs 578T PIK-93
0.04
uM
LJP5
 3
K18
 72
hr
 658 4188 3938 1.0634 1.0482
Hs 578T PIK-93
0.12
uM
LJP5
 1
K17
 72
hr
 658 3891 3908 0.9955 0.9965
Hs 578T PIK-93
0.12
uM
LJP5
 2
K17
 72
hr
 658 3968 3953 1.0036 1.0028
Hs 578T PIK-93
0.12
uM
LJP5
 3
K17
 72
hr
 658 3795 3938 0.9636 0.9715