LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T PIK-93
0.37
uM
LJP5
 1
K16
 72
hr
 658 3616 3908 0.9252 0.9404
Hs 578T PIK-93
0.37
uM
LJP5
 2
K16
 72
hr
 658 3690 3953 0.9333 0.9473
Hs 578T PIK-93
0.37
uM
LJP5
 3
K16
 72
hr
 658 3495 3938 0.8874 0.9096
Hs 578T PIK-93
1.11
uM
LJP5
 1
K15
 72
hr
 658 3095 3908 0.7919 0.8264
Hs 578T PIK-93
1.11
uM
LJP5
 2
K15
 72
hr
 658 3168 3953 0.8013 0.8358
Hs 578T PIK-93
1.11
uM
LJP5
 3
K15
 72
hr
 658 3119 3938 0.7919 0.8272
Hs 578T PIK-93
3.33
uM
LJP5
 1
K14
 72
hr
 658 2634 3908 0.6739 0.7153
Hs 578T PIK-93
3.33
uM
LJP5
 2
K14
 72
hr
 658 2604 3953 0.6586 0.7018
Hs 578T PIK-93
3.33
uM
LJP5
 3
K14
 72
hr
 658 2503 3938 0.6355 0.6779
Hs 578T PIK-93
10
uM
LJP5
 1
K13
 72
hr
 658 1304 3908 0.3336 0.3048
Hs 578T PIK-93
10
uM
LJP5
 2
K13
 72
hr
 658 1357 3953 0.3432 0.3228
Hs 578T PIK-93
10
uM
LJP5
 3
K13
 72
hr
 658 1288 3938 0.3270 0.2971
Hs 578T Dactolisib
0.04
uM
LJP5
 1
M18
 72
hr
 658 1136 3908 0.2907 0.2366
Hs 578T Dactolisib
0.04
uM
LJP5
 2
M18
 72
hr
 658 1144 3953 0.2894 0.2383
Hs 578T Dactolisib
0.04
uM
LJP5
 3
M18
 72
hr
 658 1211 3938 0.3075 0.2665
Hs 578T Dactolisib
0.12
uM
LJP5
 1
M17
 72
hr
 658 940 3908 0.2405 0.1488
Hs 578T Dactolisib
0.12
uM
LJP5
 2
M17
 72
hr
 658 1028 3953 0.2600 0.1881
Hs 578T Dactolisib
0.12
uM
LJP5
 3
M17
 72
hr
 658 973 3938 0.2471 0.1635
Hs 578T Dactolisib
0.37
uM
LJP5
 1
M16
 72
hr
 658 781 3908 0.1998 0.0688
Hs 578T Dactolisib
0.37
uM
LJP5
 2
M16
 72
hr
 658 749 3953 0.1894 0.0512
Hs 578T Dactolisib
0.37
uM
LJP5
 3
M16
 72
hr
 658 839 3938 0.2130 0.0986
Hs 578T Dactolisib
1.11
uM
LJP5
 1
M15
 72
hr
 658 966 3908 0.2472 0.1610
Hs 578T Dactolisib
1.11
uM
LJP5
 2
M15
 72
hr
 658 972 3953 0.2458 0.1627
Hs 578T Dactolisib
1.11
uM
LJP5
 3
M15
 72
hr
 658 824 3938 0.2092 0.0910
Hs 578T Dactolisib
3.33
uM
LJP5
 1
M14
 72
hr
 658 909 3908 0.2326 0.1339