LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Dactolisib
3.33
uM
LJP5
 2
M14
 72
hr
 658 919 3953 0.2324 0.1377
Hs 578T Dactolisib
3.33
uM
LJP5
 3
M14
 72
hr
 658 1009 3938 0.2562 0.1800
Hs 578T Dactolisib
10
uM
LJP5
 1
M13
 72
hr
 658 965 3908 0.2469 0.1605
Hs 578T Dactolisib
10
uM
LJP5
 2
M13
 72
hr
 658 1016 3953 0.2570 0.1828
Hs 578T Dactolisib
10
uM
LJP5
 3
M13
 72
hr
 658 932 3938 0.2366 0.1443
Hs 578T Alpelisib
0.04
uM
LJP5
 1
N06
 72
hr
 658 3794 3908 0.9707 0.9770
Hs 578T Alpelisib
0.04
uM
LJP5
 2
N06
 72
hr
 658 3945 3953 0.9978 0.9983
Hs 578T Alpelisib
0.04
uM
LJP5
 3
N06
 72
hr
 658 3766 3938 0.9562 0.9656
Hs 578T Alpelisib
0.12
uM
LJP5
 1
N05
 72
hr
 658 3541 3908 0.9060 0.9246
Hs 578T Alpelisib
0.12
uM
LJP5
 2
N05
 72
hr
 658 3619 3953 0.9153 0.9328
Hs 578T Alpelisib
0.12
uM
LJP5
 3
N05
 72
hr
 658 3391 3938 0.8610 0.8873
Hs 578T Alpelisib
0.37
uM
LJP5
 1
N04
 72
hr
 658 3356 3908 0.8586 0.8849
Hs 578T Alpelisib
0.37
uM
LJP5
 2
N04
 72
hr
 658 3318 3953 0.8392 0.8690
Hs 578T Alpelisib
0.37
uM
LJP5
 3
N04
 72
hr
 658 3381 3938 0.8585 0.8852
Hs 578T Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 658 3294 3908 0.8428 0.8712
Hs 578T Alpelisib
1.11
uM
LJP5
 2
N03
 72
hr
 658 3155 3953 0.7980 0.8329
Hs 578T Alpelisib
1.11
uM
LJP5
 3
N03
 72
hr
 658 3056 3938 0.7759 0.8128
Hs 578T Alpelisib
3.33
uM
LJP5
 1
N02
 72
hr
 658 2905 3908 0.7433 0.7819
Hs 578T Alpelisib
3.33
uM
LJP5
 2
N02
 72
hr
 658 2932 3953 0.7416 0.7817
Hs 578T Alpelisib
3.33
uM
LJP5
 3
N02
 72
hr
 658 2839 3938 0.7209 0.7618
Hs 578T Alpelisib
10
uM
LJP5
 1
N01
 72
hr
 658 2079 3908 0.5319 0.5644
Hs 578T Alpelisib
10
uM
LJP5
 2
N01
 72
hr
 658 2234 3953 0.5650 0.6039
Hs 578T Alpelisib
10
uM
LJP5
 3
N01
 72
hr
 658 2327 3938 0.5908 0.6311
Hs 578T GDC-0980
0.04
uM
LJP5
 1
K24
 72
hr
 658 2379 3908 0.6087 0.6487
Hs 578T GDC-0980
0.04
uM
LJP5
 2
K24
 72
hr
 658 2235 3953 0.5653 0.6042