LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T GDC-0980
0.04
uM
LJP5
 3
K24
 72
hr
 658 2342 3938 0.5947 0.6352
Hs 578T GDC-0980
0.12
uM
LJP5
 1
K23
 72
hr
 658 1650 3908 0.4222 0.4299
Hs 578T GDC-0980
0.12
uM
LJP5
 2
K23
 72
hr
 658 1745 3953 0.4414 0.4578
Hs 578T GDC-0980
0.12
uM
LJP5
 3
K23
 72
hr
 658 1819 3938 0.4619 0.4827
Hs 578T GDC-0980
0.37
uM
LJP5
 1
K22
 72
hr
 658 1352 3908 0.3459 0.3233
Hs 578T GDC-0980
0.37
uM
LJP5
 2
K22
 72
hr
 658 1347 3953 0.3407 0.3190
Hs 578T GDC-0980
0.37
uM
LJP5
 3
K22
 72
hr
 658 1440 3938 0.3656 0.3544
Hs 578T GDC-0980
1.11
uM
LJP5
 1
K21
 72
hr
 658 1163 3908 0.2976 0.2480
Hs 578T GDC-0980
1.11
uM
LJP5
 2
K21
 72
hr
 658 1182 3953 0.2990 0.2540
Hs 578T GDC-0980
1.11
uM
LJP5
 3
K21
 72
hr
 658 1292 3938 0.3281 0.2986
Hs 578T GDC-0980
3.33
uM
LJP5
 1
K20
 72
hr
 658 1120 3908 0.2866 0.2298
Hs 578T GDC-0980
3.33
uM
LJP5
 2
K20
 72
hr
 658 1086 3953 0.2747 0.2136
Hs 578T GDC-0980
3.33
uM
LJP5
 3
K20
 72
hr
 658 1180 3938 0.2996 0.2538
Hs 578T GDC-0980
10
uM
LJP5
 1
K19
 72
hr
 658 1058 3908 0.2707 0.2028
Hs 578T GDC-0980
10
uM
LJP5
 2
K19
 72
hr
 658 1018 3953 0.2575 0.1837
Hs 578T GDC-0980
10
uM
LJP5
 3
K19
 72
hr
 658 1078 3938 0.2737 0.2106
Hs 578T Mitoxantrone
0.04
uM
LJP6
 1
C24
 72
hr
 658 560 3705 0.1511 -0.0627
Hs 578T Mitoxantrone
0.04
uM
LJP6
 2
C24
 72
hr
 658 683 3807 0.1794 0.0147
Hs 578T Mitoxantrone
0.04
uM
LJP6
 3
C24
 72
hr
 658 574 3769 0.1523 -0.0529
Hs 578T Mitoxantrone
0.04
uM
LJP5
 1
C24
 72
hr
 658 643 3908 0.1645 -0.0090
Hs 578T Mitoxantrone
0.04
uM
LJP5
 2
C24
 72
hr
 658 715 3953 0.1808 0.0325
Hs 578T Mitoxantrone
0.04
uM
LJP5
 3
C24
 72
hr
 658 763 3938 0.1937 0.0589
Hs 578T Mitoxantrone
0.12
uM
LJP6
 1
C23
 72
hr
 658 598 3705 0.1614 -0.0377
Hs 578T Mitoxantrone
0.12
uM
LJP6
 2
C23
 72
hr
 658 549 3807 0.1442 -0.0691
Hs 578T Mitoxantrone
0.12
uM
LJP6
 3
C23
 72
hr
 658 661 3769 0.1753 0.0017