LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Y39983
10
uM
LJP6
 1
P01
 72
hr
 658 556 3705 0.1500 -0.0654
Hs 578T Y39983
10
uM
LJP6
 2
P01
 72
hr
 658 519 3807 0.1363 -0.0896
Hs 578T Y39983
10
uM
LJP6
 3
P01
 72
hr
 658 628 3769 0.1666 -0.0185
Hs 578T Nintedanib
0.04
uM
LJP6
 1
H06
 72
hr
 658 3524 3705 0.9509 0.9600
Hs 578T Nintedanib
0.04
uM
LJP6
 2
H06
 72
hr
 658 3794 3807 0.9964 0.9972
Hs 578T Nintedanib
0.04
uM
LJP6
 3
H06
 72
hr
 658 3350 3769 0.8887 0.9084
Hs 578T Nintedanib
0.12
uM
LJP6
 1
H05
 72
hr
 658 3289 3705 0.8875 0.9065
Hs 578T Nintedanib
0.12
uM
LJP6
 2
H05
 72
hr
 658 3495 3807 0.9179 0.9335
Hs 578T Nintedanib
0.12
uM
LJP6
 3
H05
 72
hr
 658 3399 3769 0.9017 0.9194
Hs 578T Nintedanib
0.37
uM
LJP6
 1
H04
 72
hr
 658 2659 3705 0.7175 0.7507
Hs 578T Nintedanib
0.37
uM
LJP6
 2
H04
 72
hr
 658 2897 3807 0.7609 0.7954
Hs 578T Nintedanib
0.37
uM
LJP6
 3
H04
 72
hr
 658 2903 3769 0.7701 0.8029
Hs 578T Nintedanib
1.11
uM
LJP6
 1
H03
 72
hr
 658 2153 3705 0.5810 0.6086
Hs 578T Nintedanib
1.11
uM
LJP6
 2
H03
 72
hr
 658 2409 3807 0.6327 0.6692
Hs 578T Nintedanib
1.11
uM
LJP6
 3
H03
 72
hr
 658 2399 3769 0.6364 0.6714
Hs 578T Nintedanib
3.33
uM
LJP6
 1
H02
 72
hr
 658 1732 3705 0.4674 0.4741
Hs 578T Nintedanib
3.33
uM
LJP6
 2
H02
 72
hr
 658 1772 3807 0.4654 0.4786
Hs 578T Nintedanib
3.33
uM
LJP6
 3
H02
 72
hr
 658 1663 3769 0.4412 0.4450
Hs 578T Nintedanib
10
uM
LJP6
 1
H01
 72
hr
 658 674 3705 0.1819 0.0096
Hs 578T Nintedanib
10
uM
LJP6
 2
H01
 72
hr
 658 677 3807 0.1778 0.0112
Hs 578T Nintedanib
10
uM
LJP6
 3
H01
 72
hr
 658 701 3769 0.1860 0.0253
Hs 578T Foretinib
0.04
uM
LJP5
 1
H12
 72
hr
 658 3955 3908 1.0119 1.0092
Hs 578T Foretinib
0.04
uM
LJP5
 2
H12
 72
hr
 658 3798 3953 0.9606 0.9692
Hs 578T Foretinib
0.04
uM
LJP5
 3
H12
 72
hr
 658 3777 3938 0.9590 0.9678
Hs 578T Foretinib
0.12
uM
LJP5
 1
H11
 72
hr
 658 3119 3908 0.7980 0.8319