LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T PI103
10
uM
LJP6
 3
I13
 72
hr
 658 938 3769 0.2488 0.1511
Hs 578T Dovitinib
0.04
uM
LJP5
 1
E24
 72
hr
 658 3095 3908 0.7919 0.8264
Hs 578T Dovitinib
0.04
uM
LJP5
 2
E24
 72
hr
 658 3315 3953 0.8385 0.8683
Hs 578T Dovitinib
0.04
uM
LJP5
 3
E24
 72
hr
 658 3155 3938 0.8011 0.8353
Hs 578T Dovitinib
0.12
uM
LJP5
 1
E23
 72
hr
 658 2070 3908 0.5296 0.5618
Hs 578T Dovitinib
0.12
uM
LJP5
 2
E23
 72
hr
 658 2369 3953 0.5992 0.6407
Hs 578T Dovitinib
0.12
uM
LJP5
 3
E23
 72
hr
 658 2229 3938 0.5660 0.6042
Hs 578T Dovitinib
0.37
uM
LJP5
 1
E22
 72
hr
 658 1051 3908 0.2689 0.1997
Hs 578T Dovitinib
0.37
uM
LJP5
 2
E22
 72
hr
 658 1127 3953 0.2851 0.2311
Hs 578T Dovitinib
0.37
uM
LJP5
 3
E22
 72
hr
 658 1133 3938 0.2877 0.2342
Hs 578T Dovitinib
1.11
uM
LJP5
 1
E21
 72
hr
 658 1001 3908 0.2561 0.1772
Hs 578T Dovitinib
1.11
uM
LJP5
 2
E21
 72
hr
 658 1015 3953 0.2567 0.1823
Hs 578T Dovitinib
1.11
uM
LJP5
 3
E21
 72
hr
 658 1071 3938 0.2719 0.2076
Hs 578T Dovitinib
3.33
uM
LJP5
 1
E20
 72
hr
 658 1138 3908 0.2912 0.2374
Hs 578T Dovitinib
3.33
uM
LJP5
 2
E20
 72
hr
 658 1227 3953 0.3103 0.2723
Hs 578T Dovitinib
3.33
uM
LJP5
 3
E20
 72
hr
 658 1248 3938 0.3169 0.2813
Hs 578T Dovitinib
10
uM
LJP5
 1
E19
 72
hr
 658 825 3908 0.2111 0.0919
Hs 578T Dovitinib
10
uM
LJP5
 2
E19
 72
hr
 658 874 3953 0.2211 0.1159
Hs 578T Dovitinib
10
uM
LJP5
 3
E19
 72
hr
 658 907 3938 0.2303 0.1323
Hs 578T GSK 690693
0.04
uM
LJP5
 1
F24
 72
hr
 658 3250 3908 0.8315 0.8615
Hs 578T GSK 690693
0.04
uM
LJP5
 2
F24
 72
hr
 658 3502 3953 0.8858 0.9084
Hs 578T GSK 690693
0.04
uM
LJP5
 3
F24
 72
hr
 658 3521 3938 0.8940 0.9150
Hs 578T GSK 690693
0.12
uM
LJP5
 1
F23
 72
hr
 658 3309 3908 0.8466 0.8745
Hs 578T GSK 690693
0.12
uM
LJP5
 2
F23
 72
hr
 658 3354 3953 0.8483 0.8768
Hs 578T GSK 690693
0.12
uM
LJP5
 3
F23
 72
hr
 658 3408 3938 0.8653 0.8910