LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Brivanib
1.11
uM
LJP5
 2
P15
 72
hr
 658 3403 3953 0.8607 0.8873
Hs 578T Brivanib
1.11
uM
LJP5
 3
P15
 72
hr
 658 3844 3938 0.9760 0.9813
Hs 578T Brivanib
3.33
uM
LJP5
 1
P14
 72
hr
 658 3558 3908 0.9103 0.9282
Hs 578T Brivanib
3.33
uM
LJP5
 2
P14
 72
hr
 658 3510 3953 0.8878 0.9100
Hs 578T Brivanib
3.33
uM
LJP5
 3
P14
 72
hr
 658 3717 3938 0.9438 0.9557
Hs 578T Brivanib
10
uM
LJP5
 1
P13
 72
hr
 658 2644 3908 0.6765 0.7178
Hs 578T Brivanib
10
uM
LJP5
 2
P13
 72
hr
 658 2720 3953 0.6880 0.7307
Hs 578T Brivanib
10
uM
LJP5
 3
P13
 72
hr
 658 2791 3938 0.7087 0.7502
Hs 578T CHIR-99021
0.04
uM
LJP6
 1
P18
 72
hr
 658 3661 3705 0.9879 0.9903
Hs 578T CHIR-99021
0.04
uM
LJP6
 2
P18
 72
hr
 658 3560 3807 0.9350 0.9476
Hs 578T CHIR-99021
0.04
uM
LJP6
 3
P18
 72
hr
 658 3485 3769 0.9245 0.9386
Hs 578T CHIR-99021
0.12
uM
LJP6
 1
P17
 72
hr
 658 3654 3705 0.9860 0.9887
Hs 578T CHIR-99021
0.12
uM
LJP6
 2
P17
 72
hr
 658 3555 3807 0.9337 0.9465
Hs 578T CHIR-99021
0.12
uM
LJP6
 3
P17
 72
hr
 658 3514 3769 0.9322 0.9450
Hs 578T CHIR-99021
0.37
uM
LJP6
 1
P16
 72
hr
 658 3803 3705 1.0262 1.0209
Hs 578T CHIR-99021
0.37
uM
LJP6
 2
P16
 72
hr
 658 3635 3807 0.9547 0.9637
Hs 578T CHIR-99021
0.37
uM
LJP6
 3
P16
 72
hr
 658 3607 3769 0.9568 0.9653
Hs 578T CHIR-99021
1.11
uM
LJP6
 1
P15
 72
hr
 658 3504 3705 0.9455 0.9556
Hs 578T CHIR-99021
1.11
uM
LJP6
 2
P15
 72
hr
 658 3785 3807 0.9941 0.9953
Hs 578T CHIR-99021
1.11
uM
LJP6
 3
P15
 72
hr
 658 3658 3769 0.9704 0.9763
Hs 578T CHIR-99021
3.33
uM
LJP6
 1
P14
 72
hr
 658 3546 3705 0.9569 0.9649
Hs 578T CHIR-99021
3.33
uM
LJP6
 2
P14
 72
hr
 658 3227 3807 0.8475 0.8735
Hs 578T CHIR-99021
3.33
uM
LJP6
 3
P14
 72
hr
 658 3438 3769 0.9120 0.9282
Hs 578T CHIR-99021
10
uM
LJP6
 1
P13
 72
hr
 658 2262 3705 0.6104 0.6407
Hs 578T CHIR-99021
10
uM
LJP6
 2
P13
 72
hr
 658 2299 3807 0.6038 0.6387