LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T GSK1059615
1.11
uM
LJP5
 1
E03
 72
hr
 658 1474 3908 0.3771 0.3685
Hs 578T GSK1059615
1.11
uM
LJP5
 2
E03
 72
hr
 658 1480 3953 0.3743 0.3679
Hs 578T GSK1059615
1.11
uM
LJP5
 3
E03
 72
hr
 658 1616 3938 0.4103 0.4162
Hs 578T GSK1059615
3.33
uM
LJP6
 1
C02
 72
hr
 658 815 3705 0.2199 0.0895
Hs 578T GSK1059615
3.33
uM
LJP6
 2
C02
 72
hr
 658 884 3807 0.2322 0.1235
Hs 578T GSK1059615
3.33
uM
LJP6
 3
C02
 72
hr
 658 882 3769 0.2340 0.1233
Hs 578T GSK1059615
3.33
uM
LJP5
 1
E02
 72
hr
 658 692 3908 0.1771 0.0197
Hs 578T GSK1059615
3.33
uM
LJP5
 2
E02
 72
hr
 658 808 3953 0.2044 0.0825
Hs 578T GSK1059615
3.33
uM
LJP5
 3
E02
 72
hr
 658 723 3938 0.1836 0.0371
Hs 578T GSK1059615
10
uM
LJP6
 1
C01
 72
hr
 658 511 3705 0.1379 -0.0965
Hs 578T GSK1059615
10
uM
LJP6
 2
C01
 72
hr
 658 377 3807 0.0990 -0.1975
Hs 578T GSK1059615
10
uM
LJP6
 3
C01
 72
hr
 658 550 3769 0.1459 -0.0688
Hs 578T GSK1059615
10
uM
LJP5
 1
E01
 72
hr
 658 243 3908 0.0622 -0.3214
Hs 578T GSK1059615
10
uM
LJP5
 2
E01
 72
hr
 658 205 3953 0.0519 -0.3630
Hs 578T GSK1059615
10
uM
LJP5
 3
E01
 72
hr
 658 222 3938 0.0564 -0.3437
Hs 578T Brivanib
0.04
uM
LJP5
 1
P18
 72
hr
 658 3718 3908 0.9513 0.9615
Hs 578T Brivanib
0.04
uM
LJP5
 2
P18
 72
hr
 658 3827 3953 0.9680 0.9750
Hs 578T Brivanib
0.04
uM
LJP5
 3
P18
 72
hr
 658 3852 3938 0.9781 0.9829
Hs 578T Brivanib
0.12
uM
LJP5
 1
P17
 72
hr
 658 3676 3908 0.9405 0.9528
Hs 578T Brivanib
0.12
uM
LJP5
 2
P17
 72
hr
 658 3508 3953 0.8873 0.9096
Hs 578T Brivanib
0.12
uM
LJP5
 3
P17
 72
hr
 658 3693 3938 0.9377 0.9508
Hs 578T Brivanib
0.37
uM
LJP5
 1
P16
 72
hr
 658 3884 3908 0.9937 0.9951
Hs 578T Brivanib
0.37
uM
LJP5
 2
P16
 72
hr
 658 3544 3953 0.8964 0.9172
Hs 578T Brivanib
0.37
uM
LJP5
 3
P16
 72
hr
 658 3780 3938 0.9598 0.9684
Hs 578T Brivanib
1.11
uM
LJP5
 1
P15
 72
hr
 658 3593 3908 0.9193 0.9356