LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Fedratinib
0.12
uM
LJP5
 3
L05
 72
hr
 658 3625 3938 0.9204 0.9368
Hs 578T Fedratinib
0.37
uM
LJP5
 1
L04
 72
hr
 658 3298 3908 0.8438 0.8721
Hs 578T Fedratinib
0.37
uM
LJP5
 2
L04
 72
hr
 658 3230 3953 0.8170 0.8496
Hs 578T Fedratinib
0.37
uM
LJP5
 3
L04
 72
hr
 658 3147 3938 0.7991 0.8335
Hs 578T Fedratinib
1.11
uM
LJP5
 1
L03
 72
hr
 658 2222 3908 0.5685 0.6055
Hs 578T Fedratinib
1.11
uM
LJP5
 2
L03
 72
hr
 658 2275 3953 0.5754 0.6152
Hs 578T Fedratinib
1.11
uM
LJP5
 3
L03
 72
hr
 658 1996 3938 0.5068 0.5370
Hs 578T Fedratinib
3.33
uM
LJP5
 1
L02
 72
hr
 658 1231 3908 0.3150 0.2759
Hs 578T Fedratinib
3.33
uM
LJP5
 2
L02
 72
hr
 658 1264 3953 0.3197 0.2870
Hs 578T Fedratinib
3.33
uM
LJP5
 3
L02
 72
hr
 658 1315 3938 0.3339 0.3075
Hs 578T Fedratinib
10
uM
LJP5
 1
L01
 72
hr
 658 352 3908 0.0901 -0.2161
Hs 578T Fedratinib
10
uM
LJP5
 2
L01
 72
hr
 658 419 3953 0.1060 -0.1602
Hs 578T Fedratinib
10
uM
LJP5
 3
L01
 72
hr
 658 349 3938 0.0886 -0.2179
Hs 578T Trametinib
0.04
uM
LJP5
 1
P24
 72
hr
 658 1127 3908 0.2884 0.2328
Hs 578T Trametinib
0.04
uM
LJP5
 2
P24
 72
hr
 658 1050 3953 0.2656 0.1979
Hs 578T Trametinib
0.04
uM
LJP5
 3
P24
 72
hr
 658 1140 3938 0.2895 0.2372
Hs 578T Trametinib
0.12
uM
LJP5
 1
P23
 72
hr
 658 942 3908 0.2410 0.1497
Hs 578T Trametinib
0.12
uM
LJP5
 2
P23
 72
hr
 658 880 3953 0.2226 0.1188
Hs 578T Trametinib
0.12
uM
LJP5
 3
P23
 72
hr
 658 1045 3938 0.2653 0.1962
Hs 578T Trametinib
0.37
uM
LJP5
 1
P22
 72
hr
 658 905 3908 0.2316 0.1319
Hs 578T Trametinib
0.37
uM
LJP5
 2
P22
 72
hr
 658 818 3953 0.2069 0.0877
Hs 578T Trametinib
0.37
uM
LJP5
 3
P22
 72
hr
 658 950 3938 0.2412 0.1528
Hs 578T Trametinib
1.11
uM
LJP5
 1
P21
 72
hr
 658 948 3908 0.2426 0.1525
Hs 578T Trametinib
1.11
uM
LJP5
 2
P21
 72
hr
 658 853 3953 0.2158 0.1054
Hs 578T Trametinib
1.11
uM
LJP5
 3
P21
 72
hr
 658 995 3938 0.2526 0.1736