LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Ruxolitinib
10
uM
LJP5
 2
O13
 72
hr
 658 2769 3953 0.7004 0.7427
Hs 578T Ruxolitinib
10
uM
LJP5
 3
O13
 72
hr
 658 2665 3938 0.6767 0.7191
Hs 578T Momelotinib
0.04
uM
LJP5
 1
P12
 72
hr
 658 3658 3908 0.9359 0.9491
Hs 578T Momelotinib
0.04
uM
LJP5
 2
P12
 72
hr
 658 3622 3953 0.9161 0.9334
Hs 578T Momelotinib
0.04
uM
LJP5
 3
P12
 72
hr
 658 3793 3938 0.9631 0.9711
Hs 578T Momelotinib
0.12
uM
LJP5
 1
P11
 72
hr
 658 3157 3908 0.8077 0.8406
Hs 578T Momelotinib
0.12
uM
LJP5
 2
P11
 72
hr
 658 3234 3953 0.8180 0.8505
Hs 578T Momelotinib
0.12
uM
LJP5
 3
P11
 72
hr
 658 3290 3938 0.8354 0.8654
Hs 578T Momelotinib
0.37
uM
LJP5
 1
P10
 72
hr
 658 2673 3908 0.6839 0.7251
Hs 578T Momelotinib
0.37
uM
LJP5
 2
P10
 72
hr
 658 2821 3953 0.7135 0.7553
Hs 578T Momelotinib
0.37
uM
LJP5
 3
P10
 72
hr
 658 2928 3938 0.7434 0.7830
Hs 578T Momelotinib
1.11
uM
LJP5
 1
P09
 72
hr
 658 2185 3908 0.5590 0.5950
Hs 578T Momelotinib
1.11
uM
LJP5
 2
P09
 72
hr
 658 2111 3953 0.5339 0.5692
Hs 578T Momelotinib
1.11
uM
LJP5
 3
P09
 72
hr
 658 2226 3938 0.5652 0.6033
Hs 578T Momelotinib
3.33
uM
LJP5
 1
P08
 72
hr
 658 1291 3908 0.3303 0.2997
Hs 578T Momelotinib
3.33
uM
LJP5
 2
P08
 72
hr
 658 1281 3953 0.3240 0.2936
Hs 578T Momelotinib
3.33
uM
LJP5
 3
P08
 72
hr
 658 1358 3938 0.3448 0.3239
Hs 578T Momelotinib
10
uM
LJP5
 1
P07
 72
hr
 658 557 3908 0.1425 -0.0629
Hs 578T Momelotinib
10
uM
LJP5
 2
P07
 72
hr
 658 498 3953 0.1260 -0.1022
Hs 578T Momelotinib
10
uM
LJP5
 3
P07
 72
hr
 658 628 3938 0.1595 -0.0180
Hs 578T Fedratinib
0.04
uM
LJP5
 1
L06
 72
hr
 658 3844 3908 0.9835 0.9871
Hs 578T Fedratinib
0.04
uM
LJP5
 2
L06
 72
hr
 658 3932 3953 0.9945 0.9958
Hs 578T Fedratinib
0.04
uM
LJP5
 3
L06
 72
hr
 658 3885 3938 0.9864 0.9894
Hs 578T Fedratinib
0.12
uM
LJP5
 1
L05
 72
hr
 658 3670 3908 0.9390 0.9516
Hs 578T Fedratinib
0.12
uM
LJP5
 2
L05
 72
hr
 658 3974 3953 1.0051 1.0040