LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Trametinib
3.33
uM
LJP5
 1
P20
 72
hr
 658 864 3908 0.2211 0.1117
Hs 578T Trametinib
3.33
uM
LJP5
 2
P20
 72
hr
 658 928 3953 0.2347 0.1420
Hs 578T Trametinib
3.33
uM
LJP5
 3
P20
 72
hr
 658 923 3938 0.2344 0.1400
Hs 578T Trametinib
10
uM
LJP5
 1
P19
 72
hr
 658 975 3908 0.2495 0.1652
Hs 578T Trametinib
10
uM
LJP5
 2
P19
 72
hr
 658 900 3953 0.2276 0.1286
Hs 578T Trametinib
10
uM
LJP5
 3
P19
 72
hr
 658 964 3938 0.2448 0.1593
Hs 578T Omipalisib
0.04
uM
LJP6
 1
N06
 72
hr
 658 1196 3705 0.3227 0.2707
Hs 578T Omipalisib
0.04
uM
LJP6
 2
N06
 72
hr
 658 1160 3807 0.3047 0.2508
Hs 578T Omipalisib
0.04
uM
LJP6
 3
N06
 72
hr
 658 1152 3769 0.3056 0.2490
Hs 578T Omipalisib
0.12
uM
LJP6
 1
N05
 72
hr
 658 903 3705 0.2437 0.1352
Hs 578T Omipalisib
0.12
uM
LJP6
 2
N05
 72
hr
 658 925 3807 0.2429 0.1438
Hs 578T Omipalisib
0.12
uM
LJP6
 3
N05
 72
hr
 658 911 3769 0.2417 0.1378
Hs 578T Omipalisib
0.37
uM
LJP6
 1
N04
 72
hr
 658 631 3705 0.1703 -0.0168
Hs 578T Omipalisib
0.37
uM
LJP6
 2
N04
 72
hr
 658 648 3807 0.1702 -0.0061
Hs 578T Omipalisib
0.37
uM
LJP6
 3
N04
 72
hr
 658 682 3769 0.1809 0.0142
Hs 578T Omipalisib
1.11
uM
LJP6
 1
N03
 72
hr
 658 514 3705 0.1387 -0.0944
Hs 578T Omipalisib
1.11
uM
LJP6
 2
N03
 72
hr
 658 540 3807 0.1418 -0.0752
Hs 578T Omipalisib
1.11
uM
LJP6
 3
N03
 72
hr
 658 496 3769 0.1316 -0.1063
Hs 578T Omipalisib
3.33
uM
LJP6
 1
N02
 72
hr
 658 469 3705 0.1266 -0.1271
Hs 578T Omipalisib
3.33
uM
LJP6
 2
N02
 72
hr
 658 448 3807 0.1177 -0.1409
Hs 578T Omipalisib
3.33
uM
LJP6
 3
N02
 72
hr
 658 392 3769 0.1040 -0.1860
Hs 578T Omipalisib
10
uM
LJP6
 1
N01
 72
hr
 658 340 3705 0.0917 -0.2327
Hs 578T Omipalisib
10
uM
LJP6
 2
N01
 72
hr
 658 373 3807 0.0980 -0.2009
Hs 578T Omipalisib
10
uM
LJP6
 3
N01
 72
hr
 658 347 3769 0.0920 -0.2245
Hs 578T Buparlisib
0.04
uM
LJP5
 1
H06
 72
hr
 658 3704 3908 0.9477 0.9586