LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T SU11274
3.33
uM
LJP5
 3
J08
 72
hr
 658 3330 3938 0.8455 0.8741
Hs 578T SU11274
10
uM
LJP5
 1
J07
 72
hr
 658 961 3908 0.2459 0.1587
Hs 578T SU11274
10
uM
LJP5
 2
J07
 72
hr
 658 965 3953 0.2441 0.1594
Hs 578T SU11274
10
uM
LJP5
 3
J07
 72
hr
 658 974 3938 0.2473 0.1640
Hs 578T Canertinib
0.04
uM
LJP6
 1
H12
 72
hr
 658 3892 3705 1.0502 1.0397
Hs 578T Canertinib
0.04
uM
LJP6
 2
H12
 72
hr
 658 3891 3807 1.0219 1.0172
Hs 578T Canertinib
0.04
uM
LJP6
 3
H12
 72
hr
 658 3931 3769 1.0428 1.0336
Hs 578T Canertinib
0.12
uM
LJP6
 1
H11
 72
hr
 658 3875 3705 1.0456 1.0361
Hs 578T Canertinib
0.12
uM
LJP6
 2
H11
 72
hr
 658 3984 3807 1.0463 1.0361
Hs 578T Canertinib
0.12
uM
LJP6
 3
H11
 72
hr
 658 3824 3769 1.0144 1.0114
Hs 578T Canertinib
0.37
uM
LJP6
 1
H10
 72
hr
 658 3757 3705 1.0138 1.0110
Hs 578T Canertinib
0.37
uM
LJP6
 2
H10
 72
hr
 658 3791 3807 0.9957 0.9966
Hs 578T Canertinib
0.37
uM
LJP6
 3
H10
 72
hr
 658 3581 3769 0.9499 0.9596
Hs 578T Canertinib
1.11
uM
LJP6
 1
H09
 72
hr
 658 3512 3705 0.9477 0.9574
Hs 578T Canertinib
1.11
uM
LJP6
 2
H09
 72
hr
 658 3571 3807 0.9379 0.9500
Hs 578T Canertinib
1.11
uM
LJP6
 3
H09
 72
hr
 658 3565 3769 0.9457 0.9561
Hs 578T Canertinib
3.33
uM
LJP6
 1
H08
 72
hr
 658 2982 3705 0.8047 0.8331
Hs 578T Canertinib
3.33
uM
LJP6
 2
H08
 72
hr
 658 3245 3807 0.8523 0.8776
Hs 578T Canertinib
3.33
uM
LJP6
 3
H08
 72
hr
 658 3070 3769 0.8144 0.8434
Hs 578T Canertinib
10
uM
LJP6
 1
H07
 72
hr
 658 332 3705 0.0896 -0.2400
Hs 578T Canertinib
10
uM
LJP6
 2
H07
 72
hr
 658 394 3807 0.1035 -0.1834
Hs 578T Canertinib
10
uM
LJP6
 3
H07
 72
hr
 658 328 3769 0.0870 -0.2417
Hs 578T NVP-AEW541
0.04
uM
LJP5
 1
E18
 72
hr
 658 4082 3908 1.0444 1.0341
Hs 578T NVP-AEW541
0.04
uM
LJP5
 2
E18
 72
hr
 658 3935 3953 0.9953 0.9963
Hs 578T NVP-AEW541
0.04
uM
LJP5
 3
E18
 72
hr
 658 3900 3938 0.9902 0.9924