LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Buparlisib
0.04
uM
LJP5
 2
H06
 72
hr
 658 3727 3953 0.9427 0.9549
Hs 578T Buparlisib
0.04
uM
LJP5
 3
H06
 72
hr
 658 3496 3938 0.8877 0.9098
Hs 578T Buparlisib
0.12
uM
LJP5
 1
H05
 72
hr
 658 3062 3908 0.7834 0.8188
Hs 578T Buparlisib
0.12
uM
LJP5
 2
H05
 72
hr
 658 3246 3953 0.8210 0.8532
Hs 578T Buparlisib
0.12
uM
LJP5
 3
H05
 72
hr
 658 3214 3938 0.8161 0.8485
Hs 578T Buparlisib
0.37
uM
LJP5
 1
H04
 72
hr
 658 2452 3908 0.6274 0.6682
Hs 578T Buparlisib
0.37
uM
LJP5
 2
H04
 72
hr
 658 2380 3953 0.6020 0.6437
Hs 578T Buparlisib
0.37
uM
LJP5
 3
H04
 72
hr
 658 2543 3938 0.6457 0.6882
Hs 578T Buparlisib
1.11
uM
LJP5
 1
H03
 72
hr
 658 1024 3908 0.2620 0.1877
Hs 578T Buparlisib
1.11
uM
LJP5
 2
H03
 72
hr
 658 1198 3953 0.3030 0.2605
Hs 578T Buparlisib
1.11
uM
LJP5
 3
H03
 72
hr
 658 1094 3938 0.2778 0.2176
Hs 578T Buparlisib
3.33
uM
LJP5
 1
H02
 72
hr
 658 433 3908 0.1108 -0.1504
Hs 578T Buparlisib
3.33
uM
LJP5
 2
H02
 72
hr
 658 515 3953 0.1303 -0.0905
Hs 578T Buparlisib
3.33
uM
LJP5
 3
H02
 72
hr
 658 484 3938 0.1229 -0.1123
Hs 578T Buparlisib
10
uM
LJP5
 1
H01
 72
hr
 658 378 3908 0.0967 -0.1941
Hs 578T Buparlisib
10
uM
LJP5
 2
H01
 72
hr
 658 382 3953 0.0966 -0.1897
Hs 578T Buparlisib
10
uM
LJP5
 3
H01
 72
hr
 658 427 3938 0.1084 -0.1544
Hs 578T XL147
0.04
uM
LJP5
 1
G12
 72
hr
 658 4033 3908 1.0319 1.0246
Hs 578T XL147
0.04
uM
LJP5
 2
G12
 72
hr
 658 3912 3953 0.9895 0.9918
Hs 578T XL147
0.04
uM
LJP5
 3
G12
 72
hr
 658 4032 3938 1.0238 1.0183
Hs 578T XL147
0.12
uM
LJP5
 1
G11
 72
hr
 658 3927 3908 1.0047 1.0037
Hs 578T XL147
0.12
uM
LJP5
 2
G11
 72
hr
 658 4017 3953 1.0160 1.0123
Hs 578T XL147
0.12
uM
LJP5
 3
G11
 72
hr
 658 3897 3938 0.9895 0.9918
Hs 578T XL147
0.37
uM
LJP5
 1
G10
 72
hr
 658 3859 3908 0.9873 0.9901
Hs 578T XL147
0.37
uM
LJP5
 2
G10
 72
hr
 658 3932 3953 0.9945 0.9958