LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Celastrol
1.11
uM
LJP6
 1
G09
 72
hr
 1235 761 4355 0.1747 -0.2342
MDA-MB-231 Celastrol
1.11
uM
LJP6
 2
G09
 72
hr
 1235 997 4277 0.2331 -0.1130
MDA-MB-231 Celastrol
1.11
uM
LJP6
 3
G09
 72
hr
 1235 799 4583 0.1743 -0.2060
MDA-MB-231 Celastrol
3.33
uM
LJP6
 1
G08
 72
hr
 1235 738 4355 0.1694 -0.2470
MDA-MB-231 Celastrol
3.33
uM
LJP6
 2
G08
 72
hr
 1235 819 4277 0.1915 -0.2053
MDA-MB-231 Celastrol
3.33
uM
LJP6
 3
G08
 72
hr
 1235 783 4583 0.1708 -0.2145
MDA-MB-231 Celastrol
10
uM
LJP6
 1
G07
 72
hr
 1235 191 4355 0.0438 -0.6421
MDA-MB-231 Celastrol
10
uM
LJP6
 2
G07
 72
hr
 1235 255 4277 0.0596 -0.5857
MDA-MB-231 Celastrol
10
uM
LJP6
 3
G07
 72
hr
 1235 332 4583 0.0724 -0.5010
MDA-MB-231 SU11274
0.04
uM
LJP5
 1
J12
 72
hr
 1235 4460 4474 0.9967 0.9965
MDA-MB-231 SU11274
0.04
uM
LJP5
 2
J12
 72
hr
 1235 4651 4578 1.0158 1.0167
MDA-MB-231 SU11274
0.04
uM
LJP5
 3
J12
 72
hr
 1235 4956 4929 1.0054 1.0054
MDA-MB-231 SU11274
0.12
uM
LJP5
 1
J11
 72
hr
 1235 4147 4474 0.9268 0.9197
MDA-MB-231 SU11274
0.12
uM
LJP5
 2
J11
 72
hr
 1235 4526 4578 0.9885 0.9878
MDA-MB-231 SU11274
0.12
uM
LJP5
 3
J11
 72
hr
 1235 4890 4929 0.9920 0.9920
MDA-MB-231 SU11274
0.37
uM
LJP5
 1
J10
 72
hr
 1235 3976 4474 0.8886 0.8767
MDA-MB-231 SU11274
0.37
uM
LJP5
 2
J10
 72
hr
 1235 4575 4578 0.9992 0.9992
MDA-MB-231 SU11274
0.37
uM
LJP5
 3
J10
 72
hr
 1235 4736 4929 0.9608 0.9603
MDA-MB-231 SU11274
1.11
uM
LJP5
 1
J09
 72
hr
 1235 3888 4474 0.8689 0.8542
MDA-MB-231 SU11274
1.11
uM
LJP5
 2
J09
 72
hr
 1235 4236 4578 0.9252 0.9194
MDA-MB-231 SU11274
1.11
uM
LJP5
 3
J09
 72
hr
 1235 4406 4929 0.8938 0.8906
MDA-MB-231 SU11274
3.33
uM
LJP5
 1
J08
 72
hr
 1235 3441 4474 0.7690 0.7361
MDA-MB-231 SU11274
3.33
uM
LJP5
 2
J08
 72
hr
 1235 3585 4578 0.7830 0.7571
MDA-MB-231 SU11274
3.33
uM
LJP5
 3
J08
 72
hr
 1235 3992 4929 0.8099 0.7994
MDA-MB-231 SU11274
10
uM
LJP5
 1
J07
 72
hr
 1235 1095 4474 0.2447 -0.0632