LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PF431396
0.04
uM
LJP5
 3
E12
 72
hr
 1235 3942 4929 0.7997 0.7881
MDA-MB-231 PF431396
0.12
uM
LJP5
 1
E11
 72
hr
 1235 3268 4474 0.7303 0.6885
MDA-MB-231 PF431396
0.12
uM
LJP5
 2
E11
 72
hr
 1235 3547 4578 0.7747 0.7472
MDA-MB-231 PF431396
0.12
uM
LJP5
 3
E11
 72
hr
 1235 3356 4929 0.6808 0.6496
MDA-MB-231 PF431396
0.37
uM
LJP5
 1
E10
 72
hr
 1235 1799 4474 0.4020 0.2241
MDA-MB-231 PF431396
0.37
uM
LJP5
 2
E10
 72
hr
 1235 1996 4578 0.4359 0.2888
MDA-MB-231 PF431396
0.37
uM
LJP5
 3
E10
 72
hr
 1235 1949 4929 0.3954 0.2564
MDA-MB-231 PF431396
1.11
uM
LJP5
 1
E09
 72
hr
 1235 1570 4474 0.3509 0.1376
MDA-MB-231 PF431396
1.11
uM
LJP5
 2
E09
 72
hr
 1235 1491 4578 0.3257 0.1044
MDA-MB-231 PF431396
1.11
uM
LJP5
 3
E09
 72
hr
 1235 1545 4929 0.3134 0.1183
MDA-MB-231 PF431396
3.33
uM
LJP5
 1
E08
 72
hr
 1235 1223 4474 0.2733 -0.0057
MDA-MB-231 PF431396
3.33
uM
LJP5
 2
E08
 72
hr
 1235 1311 4578 0.2863 0.0317
MDA-MB-231 PF431396
3.33
uM
LJP5
 3
E08
 72
hr
 1235 1281 4929 0.2599 0.0181
MDA-MB-231 PF431396
10
uM
LJP5
 1
E07
 72
hr
 1235 470 4474 0.1050 -0.4060
MDA-MB-231 PF431396
10
uM
LJP5
 2
E07
 72
hr
 1235 394 4578 0.0861 -0.4540
MDA-MB-231 PF431396
10
uM
LJP5
 3
E07
 72
hr
 1235 435 4929 0.0882 -0.4074
MDA-MB-231 Celastrol
0.04
uM
LJP6
 1
G12
 72
hr
 1235 4804 4355 1.1029 1.1107
MDA-MB-231 Celastrol
0.04
uM
LJP6
 2
G12
 72
hr
 1235 5367 4277 1.2547 1.2702
MDA-MB-231 Celastrol
0.04
uM
LJP6
 3
G12
 72
hr
 1235 5038 4583 1.0992 1.1026
MDA-MB-231 Celastrol
0.12
uM
LJP6
 1
G11
 72
hr
 1235 4236 4355 0.9725 0.9695
MDA-MB-231 Celastrol
0.12
uM
LJP6
 2
G11
 72
hr
 1235 5134 4277 1.2003 1.2146
MDA-MB-231 Celastrol
0.12
uM
LJP6
 3
G11
 72
hr
 1235 4817 4583 1.0510 1.0533
MDA-MB-231 Celastrol
0.37
uM
LJP6
 1
G10
 72
hr
 1235 3330 4355 0.7645 0.7252
MDA-MB-231 Celastrol
0.37
uM
LJP6
 2
G10
 72
hr
 1235 3584 4277 0.8379 0.8120
MDA-MB-231 Celastrol
0.37
uM
LJP6
 3
G10
 72
hr
 1235 3855 4583 0.8411 0.8251