LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Momelotinib
0.04
uM
LJP5
 1
P12
 72
hr
 1235 3910 4474 0.8738 0.8598
MDA-MB-231 Momelotinib
0.04
uM
LJP5
 2
P12
 72
hr
 1235 3843 4578 0.8393 0.8229
MDA-MB-231 Momelotinib
0.04
uM
LJP5
 3
P12
 72
hr
 1235 4524 4929 0.9178 0.9158
MDA-MB-231 Momelotinib
0.12
uM
LJP5
 1
P11
 72
hr
 1235 3351 4474 0.7489 0.7115
MDA-MB-231 Momelotinib
0.12
uM
LJP5
 2
P11
 72
hr
 1235 3183 4578 0.6952 0.6499
MDA-MB-231 Momelotinib
0.12
uM
LJP5
 3
P11
 72
hr
 1235 4163 4929 0.8445 0.8377
MDA-MB-231 Momelotinib
0.37
uM
LJP5
 1
P10
 72
hr
 1235 2758 4474 0.6164 0.5410
MDA-MB-231 Momelotinib
0.37
uM
LJP5
 2
P10
 72
hr
 1235 2836 4578 0.6194 0.5521
MDA-MB-231 Momelotinib
0.37
uM
LJP5
 3
P10
 72
hr
 1235 3317 4929 0.6729 0.6399
MDA-MB-231 Momelotinib
1.11
uM
LJP5
 1
P09
 72
hr
 1235 1925 4474 0.4302 0.2696
MDA-MB-231 Momelotinib
1.11
uM
LJP5
 2
P09
 72
hr
 1235 1997 4578 0.4362 0.2891
MDA-MB-231 Momelotinib
1.11
uM
LJP5
 3
P09
 72
hr
 1235 2404 4929 0.4877 0.3956
MDA-MB-231 Momelotinib
3.33
uM
LJP5
 1
P08
 72
hr
 1235 1222 4474 0.2731 -0.0061
MDA-MB-231 Momelotinib
3.33
uM
LJP5
 2
P08
 72
hr
 1235 1308 4578 0.2857 0.0304
MDA-MB-231 Momelotinib
3.33
uM
LJP5
 3
P08
 72
hr
 1235 1488 4929 0.3019 0.0975
MDA-MB-231 Momelotinib
10
uM
LJP5
 1
P07
 72
hr
 1235 483 4474 0.1079 -0.3972
MDA-MB-231 Momelotinib
10
uM
LJP5
 2
P07
 72
hr
 1235 565 4578 0.1234 -0.3392
MDA-MB-231 Momelotinib
10
uM
LJP5
 3
P07
 72
hr
 1235 675 4929 0.1369 -0.2615
MDA-MB-231 Fedratinib
0.04
uM
LJP5
 1
L06
 72
hr
 1235 3943 4474 0.8812 0.8682
MDA-MB-231 Fedratinib
0.04
uM
LJP5
 2
L06
 72
hr
 1235 4326 4578 0.9448 0.9408
MDA-MB-231 Fedratinib
0.04
uM
LJP5
 3
L06
 72
hr
 1235 4900 4929 0.9941 0.9940
MDA-MB-231 Fedratinib
0.12
uM
LJP5
 1
L05
 72
hr
 1235 3568 4474 0.7974 0.7703
MDA-MB-231 Fedratinib
0.12
uM
LJP5
 2
L05
 72
hr
 1235 4027 4578 0.8795 0.8686
MDA-MB-231 Fedratinib
0.12
uM
LJP5
 3
L05
 72
hr
 1235 4511 4929 0.9151 0.9131
MDA-MB-231 Fedratinib
0.37
uM
LJP5
 1
L04
 72
hr
 1235 3096 4474 0.6919 0.6400