LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 2
N16
 72
hr
 1235 4235 4578 0.9250 0.9191
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 3
N16
 72
hr
 1235 4820 4929 0.9778 0.9777
MDA-MB-231 Nilotinib
1.11
uM
LJP5
 1
N15
 72
hr
 1235 3679 4474 0.8222 0.7998
MDA-MB-231 Nilotinib
1.11
uM
LJP5
 2
N15
 72
hr
 1235 3880 4578 0.8474 0.8322
MDA-MB-231 Nilotinib
1.11
uM
LJP5
 3
N15
 72
hr
 1235 4766 4929 0.9669 0.9665
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 1
N14
 72
hr
 1235 3888 4474 0.8689 0.8542
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 2
N14
 72
hr
 1235 4012 4578 0.8763 0.8649
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 3
N14
 72
hr
 1235 4614 4929 0.9360 0.9349
MDA-MB-231 Nilotinib
10
uM
LJP5
 1
N13
 72
hr
 1235 951 4474 0.2125 -0.1317
MDA-MB-231 Nilotinib
10
uM
LJP5
 2
N13
 72
hr
 1235 1006 4578 0.2197 -0.1032
MDA-MB-231 Nilotinib
10
uM
LJP5
 3
N13
 72
hr
 1235 1057 4929 0.2144 -0.0754
MDA-MB-231 JNK-9L
0.04
uM
LJP6
 1
K24
 72
hr
 1235 3870 4355 0.8884 0.8740
MDA-MB-231 JNK-9L
0.04
uM
LJP6
 2
K24
 72
hr
 1235 3735 4277 0.8732 0.8542
MDA-MB-231 JNK-9L
0.04
uM
LJP6
 3
K24
 72
hr
 1235 4042 4583 0.8819 0.8714
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 1
K23
 72
hr
 1235 3271 4355 0.7509 0.7084
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 2
K23
 72
hr
 1235 3410 4277 0.7972 0.7623
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 3
K23
 72
hr
 1235 3896 4583 0.8500 0.8353
MDA-MB-231 JNK-9L
0.37
uM
LJP6
 1
K22
 72
hr
 1235 2051 4355 0.4709 0.3214
MDA-MB-231 JNK-9L
0.37
uM
LJP6
 2
K22
 72
hr
 1235 2245 4277 0.5249 0.3955
MDA-MB-231 JNK-9L
0.37
uM
LJP6
 3
K22
 72
hr
 1235 2548 4583 0.5559 0.4661
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 1
K21
 72
hr
 1235 890 4355 0.2043 -0.1653
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 2
K21
 72
hr
 1235 778 4277 0.1819 -0.2277
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 3
K21
 72
hr
 1235 922 4583 0.2012 -0.1436
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 1
K20
 72
hr
 1235 693 4355 0.1591 -0.2727
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 2
K20
 72
hr
 1235 641 4277 0.1499 -0.3069