LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Palbociclib
1.11
uM
LJP6
 1
E15
 72
hr
 1235 2084 4355 0.4784 0.3331
MDA-MB-231 Palbociclib
1.11
uM
LJP6
 2
E15
 72
hr
 1235 2199 4277 0.5141 0.3794
MDA-MB-231 Palbociclib
1.11
uM
LJP6
 3
E15
 72
hr
 1235 2411 4583 0.5260 0.4239
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 1
E14
 72
hr
 1235 1891 4355 0.4341 0.2637
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 2
E14
 72
hr
 1235 2253 4277 0.5267 0.3983
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 3
E14
 72
hr
 1235 2087 4583 0.4553 0.3193
MDA-MB-231 Palbociclib
10
uM
LJP6
 1
E13
 72
hr
 1235 1788 4355 0.4105 0.2253
MDA-MB-231 Palbociclib
10
uM
LJP6
 2
E13
 72
hr
 1235 1954 4277 0.4568 0.2914
MDA-MB-231 Palbociclib
10
uM
LJP6
 3
E13
 72
hr
 1235 1696 4583 0.3700 0.1822
MDA-MB-231 PF562271
0.04
uM
LJP6
 1
F18
 72
hr
 1235 3742 4355 0.8591 0.8396
MDA-MB-231 PF562271
0.04
uM
LJP6
 2
F18
 72
hr
 1235 3945 4277 0.9223 0.9117
MDA-MB-231 PF562271
0.04
uM
LJP6
 3
F18
 72
hr
 1235 3940 4583 0.8596 0.8462
MDA-MB-231 PF562271
0.12
uM
LJP6
 1
F17
 72
hr
 1235 3237 4355 0.7431 0.6986
MDA-MB-231 PF562271
0.12
uM
LJP6
 2
F17
 72
hr
 1235 3283 4277 0.7675 0.7254
MDA-MB-231 PF562271
0.12
uM
LJP6
 3
F17
 72
hr
 1235 3640 4583 0.7942 0.7705
MDA-MB-231 PF562271
0.37
uM
LJP6
 1
F16
 72
hr
 1235 2949 4355 0.6770 0.6137
MDA-MB-231 PF562271
0.37
uM
LJP6
 2
F16
 72
hr
 1235 2999 4277 0.7011 0.6404
MDA-MB-231 PF562271
0.37
uM
LJP6
 3
F16
 72
hr
 1235 3402 4583 0.7423 0.7083
MDA-MB-231 PF562271
1.11
uM
LJP6
 1
F15
 72
hr
 1235 2257 4355 0.5181 0.3929
MDA-MB-231 PF562271
1.11
uM
LJP6
 2
F15
 72
hr
 1235 2355 4277 0.5506 0.4333
MDA-MB-231 PF562271
1.11
uM
LJP6
 3
F15
 72
hr
 1235 2451 4583 0.5348 0.4363
MDA-MB-231 PF562271
3.33
uM
LJP6
 1
F14
 72
hr
 1235 1186 4355 0.2723 -0.0224
MDA-MB-231 PF562271
3.33
uM
LJP6
 2
F14
 72
hr
 1235 1153 4277 0.2696 -0.0380
MDA-MB-231 PF562271
3.33
uM
LJP6
 3
F14
 72
hr
 1235 1435 4583 0.3131 0.0822
MDA-MB-231 PF562271
10
uM
LJP6
 1
F13
 72
hr
 1235 439 4355 0.1008 -0.4342