LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 1
N12
 72
hr
 1235 4351 4355 0.9989 0.9988
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 2
N12
 72
hr
 1235 4533 4277 1.0598 1.0659
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 3
N12
 72
hr
 1235 4567 4583 0.9964 0.9962
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 1
N11
 72
hr
 1235 4385 4355 1.0067 1.0073
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 2
N11
 72
hr
 1235 4226 4277 0.9880 0.9866
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 3
N11
 72
hr
 1235 4185 4583 0.9131 0.9061
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 1
N10
 72
hr
 1235 4630 4355 1.0629 1.0683
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 2
N10
 72
hr
 1235 4412 4277 1.0315 1.0349
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 3
N10
 72
hr
 1235 4289 4583 0.9358 0.9310
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 1
N09
 72
hr
 1235 4416 4355 1.0138 1.0151
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 2
N09
 72
hr
 1235 4481 4277 1.0476 1.0526
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 3
N09
 72
hr
 1235 4190 4583 0.9142 0.9073
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 1
N08
 72
hr
 1235 4115 4355 0.9447 0.9384
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 2
N08
 72
hr
 1235 4256 4277 0.9950 0.9944
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 3
N08
 72
hr
 1235 4119 4583 0.8987 0.8901
MDA-MB-231 Gefitinib
10
uM
LJP6
 1
N07
 72
hr
 1235 3943 4355 0.9052 0.8933
MDA-MB-231 Gefitinib
10
uM
LJP6
 2
N07
 72
hr
 1235 3861 4277 0.9027 0.8889
MDA-MB-231 Gefitinib
10
uM
LJP6
 3
N07
 72
hr
 1235 4041 4583 0.8817 0.8711
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 1
N18
 72
hr
 1235 4005 4474 0.8950 0.8840
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 2
N18
 72
hr
 1235 4272 4578 0.9330 0.9280
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 3
N18
 72
hr
 1235 5057 4929 1.0259 1.0258
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 1
N17
 72
hr
 1235 3938 4474 0.8801 0.8670
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 2
N17
 72
hr
 1235 4361 4578 0.9525 0.9491
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 3
N17
 72
hr
 1235 4950 4929 1.0042 1.0042
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 1
N16
 72
hr
 1235 3841 4474 0.8584 0.8420