LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 3
K20
 72
hr
 1235 729 4583 0.1591 -0.2436
MDA-MB-231 JNK-9L
10
uM
LJP6
 1
K19
 72
hr
 1235 562 4355 0.1290 -0.3519
MDA-MB-231 JNK-9L
10
uM
LJP6
 2
K19
 72
hr
 1235 523 4277 0.1223 -0.3813
MDA-MB-231 JNK-9L
10
uM
LJP6
 3
K19
 72
hr
 1235 540 4583 0.1178 -0.3546
MDA-MB-231 PD0325901
0.04
uM
LJP6
 1
E06
 72
hr
 1235 3070 4355 0.7048 0.6498
MDA-MB-231 PD0325901
0.04
uM
LJP6
 2
E06
 72
hr
 1235 2640 4277 0.6172 0.5277
MDA-MB-231 PD0325901
0.04
uM
LJP6
 3
E06
 72
hr
 1235 3243 4583 0.7076 0.6656
MDA-MB-231 PD0325901
0.04
uM
LJP5
 1
C06
 72
hr
 1235 3356 4474 0.7500 0.7128
MDA-MB-231 PD0325901
0.04
uM
LJP5
 2
C06
 72
hr
 1235 3302 4578 0.7212 0.6823
MDA-MB-231 PD0325901
0.04
uM
LJP5
 3
C06
 72
hr
 1235 3416 4929 0.6930 0.6643
MDA-MB-231 PD0325901
0.12
uM
LJP6
 1
E05
 72
hr
 1235 2550 4355 0.5854 0.4896
MDA-MB-231 PD0325901
0.12
uM
LJP6
 2
E05
 72
hr
 1235 2281 4277 0.5333 0.4079
MDA-MB-231 PD0325901
0.12
uM
LJP6
 3
E05
 72
hr
 1235 2453 4583 0.5352 0.4370
MDA-MB-231 PD0325901
0.12
uM
LJP5
 1
C05
 72
hr
 1235 2559 4474 0.5719 0.4801
MDA-MB-231 PD0325901
0.12
uM
LJP5
 2
C05
 72
hr
 1235 2298 4578 0.5019 0.3886
MDA-MB-231 PD0325901
0.12
uM
LJP5
 3
C05
 72
hr
 1235 2554 4929 0.5181 0.4386
MDA-MB-231 PD0325901
0.37
uM
LJP6
 1
E04
 72
hr
 1235 1876 4355 0.4307 0.2581
MDA-MB-231 PD0325901
0.37
uM
LJP6
 2
E04
 72
hr
 1235 1643 4277 0.3841 0.1723
MDA-MB-231 PD0325901
0.37
uM
LJP6
 3
E04
 72
hr
 1235 1881 4583 0.4104 0.2487
MDA-MB-231 PD0325901
0.37
uM
LJP5
 1
C04
 72
hr
 1235 1800 4474 0.4023 0.2245
MDA-MB-231 PD0325901
0.37
uM
LJP5
 2
C04
 72
hr
 1235 1734 4578 0.3787 0.1963
MDA-MB-231 PD0325901
0.37
uM
LJP5
 3
C04
 72
hr
 1235 2009 4929 0.4076 0.2756
MDA-MB-231 PD0325901
1.11
uM
LJP6
 1
E03
 72
hr
 1235 1151 4355 0.2642 -0.0384
MDA-MB-231 PD0325901
1.11
uM
LJP6
 2
E03
 72
hr
 1235 682 4277 0.1594 -0.2825
MDA-MB-231 PD0325901
1.11
uM
LJP6
 3
E03
 72
hr
 1235 1375 4583 0.3000 0.0580