LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Erlotinib
10
uM
LJP5
 3
M19
 72
hr
 1311 3753 5010 0.7490 0.7223
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 1
N12
 72
hr
 1311 5178 4870 1.0632 1.0658
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 2
N12
 72
hr
 1311 4899 4961 0.9874 0.9868
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 3
N12
 72
hr
 1311 5275 4973 1.0606 1.0621
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 1
N11
 72
hr
 1311 5000 4870 1.0266 1.0280
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 2
N11
 72
hr
 1311 4675 4961 0.9422 0.9389
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 3
N11
 72
hr
 1311 5386 4973 1.0829 1.0846
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 1
N10
 72
hr
 1311 5058 4870 1.0386 1.0404
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 2
N10
 72
hr
 1311 4828 4961 0.9731 0.9718
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 3
N10
 72
hr
 1311 5149 4973 1.0352 1.0363
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 1
N09
 72
hr
 1311 4960 4870 1.0184 1.0194
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 2
N09
 72
hr
 1311 4629 4961 0.9330 0.9290
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 3
N09
 72
hr
 1311 5286 4973 1.0628 1.0643
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 1
N08
 72
hr
 1311 5012 4870 1.0291 1.0306
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 2
N08
 72
hr
 1311 4787 4961 0.9648 0.9630
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 3
N08
 72
hr
 1311 5102 4973 1.0258 1.0266
MDA-MB-231 Gefitinib
10
uM
LJP6
 1
N07
 72
hr
 1311 4507 4870 0.9254 0.9198
MDA-MB-231 Gefitinib
10
uM
LJP6
 2
N07
 72
hr
 1311 4533 4961 0.9136 0.9080
MDA-MB-231 Gefitinib
10
uM
LJP6
 3
N07
 72
hr
 1311 4668 4973 0.9385 0.9351
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 1
N18
 72
hr
 1311 5011 5128 0.9771 0.9766
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 2
N18
 72
hr
 1311 4837 5100 0.9484 0.9467
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 3
N18
 72
hr
 1311 5095 5010 1.0168 1.0173
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 1
N17
 72
hr
 1311 5097 5128 0.9939 0.9938
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 2
N17
 72
hr
 1311 4906 5100 0.9620 0.9608
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 3
N17
 72
hr
 1311 5196 5010 1.0369 1.0379