LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 1
N16
 72
hr
 1311 4813 5128 0.9385 0.9365
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 2
N16
 72
hr
 1311 4450 5100 0.8726 0.8656
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 3
N16
 72
hr
 1311 4945 5010 0.9869 0.9864
MDA-MB-231 Nilotinib
1.11
uM
LJP5
 1
N15
 72
hr
 1311 4654 5128 0.9075 0.9037
MDA-MB-231 Nilotinib
1.11
uM
LJP5
 2
N15
 72
hr
 1311 4531 5100 0.8884 0.8828
MDA-MB-231 Nilotinib
1.11
uM
LJP5
 3
N15
 72
hr
 1311 4719 5010 0.9418 0.9389
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 1
N14
 72
hr
 1311 4648 5128 0.9063 0.9025
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 2
N14
 72
hr
 1311 4413 5100 0.8653 0.8576
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 3
N14
 72
hr
 1311 4795 5010 0.9569 0.9550
MDA-MB-231 Nilotinib
10
uM
LJP5
 1
N13
 72
hr
 1311 1295 5128 0.2525 -0.0065
MDA-MB-231 Nilotinib
10
uM
LJP5
 2
N13
 72
hr
 1311 1074 5100 0.2106 -0.0970
MDA-MB-231 Nilotinib
10
uM
LJP5
 3
N13
 72
hr
 1311 1119 5010 0.2233 -0.0789
MDA-MB-231 JNK-9L
0.04
uM
LJP6
 1
K24
 72
hr
 1311 4146 4870 0.8513 0.8369
MDA-MB-231 JNK-9L
0.04
uM
LJP6
 2
K24
 72
hr
 1311 4276 4961 0.8618 0.8509
MDA-MB-231 JNK-9L
0.04
uM
LJP6
 3
K24
 72
hr
 1311 3986 4973 0.8014 0.7825
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 1
K23
 72
hr
 1311 3638 4870 0.7470 0.7143
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 2
K23
 72
hr
 1311 3800 4961 0.7659 0.7405
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 3
K23
 72
hr
 1311 3974 4973 0.7990 0.7797
MDA-MB-231 JNK-9L
0.37
uM
LJP6
 1
K22
 72
hr
 1311 3035 4870 0.6232 0.5578
MDA-MB-231 JNK-9L
0.37
uM
LJP6
 2
K22
 72
hr
 1311 2709 4961 0.5460 0.4592
MDA-MB-231 JNK-9L
0.37
uM
LJP6
 3
K22
 72
hr
 1311 3058 4973 0.6148 0.5530
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 1
K21
 72
hr
 1311 1668 4870 0.3425 0.1354
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 2
K21
 72
hr
 1311 1633 4961 0.3291 0.1209
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 3
K21
 72
hr
 1311 1723 4973 0.3464 0.1524
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 1
K20
 72
hr
 1311 1149 4870 0.2359 -0.0676