LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 3
E16
 72
hr
 1311 2915 4973 0.5861 0.5148
MDA-MB-231 Palbociclib
1.11
uM
LJP6
 1
E15
 72
hr
 1311 2618 4870 0.5376 0.4407
MDA-MB-231 Palbociclib
1.11
uM
LJP6
 2
E15
 72
hr
 1311 2827 4961 0.5698 0.4919
MDA-MB-231 Palbociclib
1.11
uM
LJP6
 3
E15
 72
hr
 1311 2631 4973 0.5290 0.4362
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 1
E14
 72
hr
 1311 2357 4870 0.4840 0.3630
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 2
E14
 72
hr
 1311 2517 4961 0.5073 0.4043
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 3
E14
 72
hr
 1311 2404 4973 0.4833 0.3703
MDA-MB-231 Palbociclib
10
uM
LJP6
 1
E13
 72
hr
 1311 2181 4870 0.4478 0.3082
MDA-MB-231 Palbociclib
10
uM
LJP6
 2
E13
 72
hr
 1311 2207 4961 0.4448 0.3114
MDA-MB-231 Palbociclib
10
uM
LJP6
 3
E13
 72
hr
 1311 2071 4973 0.4164 0.2681
MDA-MB-231 PF562271
0.04
uM
LJP6
 1
F18
 72
hr
 1311 4476 4870 0.9191 0.9128
MDA-MB-231 PF562271
0.04
uM
LJP6
 2
F18
 72
hr
 1311 4646 4961 0.9364 0.9327
MDA-MB-231 PF562271
0.04
uM
LJP6
 3
F18
 72
hr
 1311 4504 4973 0.9056 0.8994
MDA-MB-231 PF562271
0.12
uM
LJP6
 1
F17
 72
hr
 1311 4048 4870 0.8312 0.8138
MDA-MB-231 PF562271
0.12
uM
LJP6
 2
F17
 72
hr
 1311 4798 4961 0.9670 0.9654
MDA-MB-231 PF562271
0.12
uM
LJP6
 3
F17
 72
hr
 1311 4316 4973 0.8678 0.8578
MDA-MB-231 PF562271
0.37
uM
LJP6
 1
F16
 72
hr
 1311 3848 4870 0.7901 0.7659
MDA-MB-231 PF562271
0.37
uM
LJP6
 2
F16
 72
hr
 1311 4233 4961 0.8531 0.8412
MDA-MB-231 PF562271
0.37
uM
LJP6
 3
F16
 72
hr
 1311 3838 4973 0.7717 0.7478
MDA-MB-231 PF562271
1.11
uM
LJP6
 1
F15
 72
hr
 1311 3387 4870 0.6955 0.6508
MDA-MB-231 PF562271
1.11
uM
LJP6
 2
F15
 72
hr
 1311 3794 4961 0.7647 0.7391
MDA-MB-231 PF562271
1.11
uM
LJP6
 3
F15
 72
hr
 1311 3268 4973 0.6570 0.6076
MDA-MB-231 PF562271
3.33
uM
LJP6
 1
F14
 72
hr
 1311 1992 4870 0.4090 0.2470
MDA-MB-231 PF562271
3.33
uM
LJP6
 2
F14
 72
hr
 1311 1978 4961 0.3987 0.2386
MDA-MB-231 PF562271
3.33
uM
LJP6
 3
F14
 72
hr
 1311 1894 4973 0.3808 0.2105