LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 SU11274
10
uM
LJP5
 1
J07
 72
hr
 1311 1770 5128 0.3451 0.1646
MDA-MB-231 SU11274
10
uM
LJP5
 2
J07
 72
hr
 1311 1492 5100 0.2926 0.0679
MDA-MB-231 SU11274
10
uM
LJP5
 3
J07
 72
hr
 1311 1705 5010 0.3403 0.1452
MDA-MB-231 Canertinib
0.04
uM
LJP6
 1
H12
 72
hr
 1311 5201 4870 1.0679 1.0707
MDA-MB-231 Canertinib
0.04
uM
LJP6
 2
H12
 72
hr
 1311 5135 4961 1.0349 1.0361
MDA-MB-231 Canertinib
0.04
uM
LJP6
 3
H12
 72
hr
 1311 4972 4973 0.9996 0.9996
MDA-MB-231 Canertinib
0.12
uM
LJP6
 1
H11
 72
hr
 1311 4826 4870 0.9909 0.9904
MDA-MB-231 Canertinib
0.12
uM
LJP6
 2
H11
 72
hr
 1311 4916 4961 0.9908 0.9904
MDA-MB-231 Canertinib
0.12
uM
LJP6
 3
H11
 72
hr
 1311 4614 4973 0.9277 0.9234
MDA-MB-231 Canertinib
0.37
uM
LJP6
 1
H10
 72
hr
 1311 4583 4870 0.9410 0.9368
MDA-MB-231 Canertinib
0.37
uM
LJP6
 2
H10
 72
hr
 1311 4808 4961 0.9690 0.9675
MDA-MB-231 Canertinib
0.37
uM
LJP6
 3
H10
 72
hr
 1311 4539 4973 0.9126 0.9071
MDA-MB-231 Canertinib
1.11
uM
LJP6
 1
H09
 72
hr
 1311 4324 4870 0.8879 0.8782
MDA-MB-231 Canertinib
1.11
uM
LJP6
 2
H09
 72
hr
 1311 4031 4961 0.8124 0.7949
MDA-MB-231 Canertinib
1.11
uM
LJP6
 3
H09
 72
hr
 1311 3965 4973 0.7972 0.7776
MDA-MB-231 Canertinib
3.33
uM
LJP6
 1
H08
 72
hr
 1311 3487 4870 0.7160 0.6763
MDA-MB-231 Canertinib
3.33
uM
LJP6
 2
H08
 72
hr
 1311 3411 4961 0.6875 0.6453
MDA-MB-231 Canertinib
3.33
uM
LJP6
 3
H08
 72
hr
 1311 3299 4973 0.6633 0.6155
MDA-MB-231 Canertinib
10
uM
LJP6
 1
H07
 72
hr
 1311 661 4870 0.1357 -0.3038
MDA-MB-231 Canertinib
10
uM
LJP6
 2
H07
 72
hr
 1311 678 4961 0.1367 -0.2910
MDA-MB-231 Canertinib
10
uM
LJP6
 3
H07
 72
hr
 1311 760 4973 0.1528 -0.2471
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 1
E18
 72
hr
 1311 4720 5128 0.9204 0.9174
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 2
E18
 72
hr
 1311 5188 5100 1.0173 1.0175
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 3
E18
 72
hr
 1311 4816 5010 0.9611 0.9594
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 1
E17
 72
hr
 1311 4785 5128 0.9331 0.9308