LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 XMD16-144
1.11
uM
LJP5
 2
M09
 72
hr
 1311 1547 5100 0.3033 0.0879
MDA-MB-231 XMD16-144
1.11
uM
LJP5
 3
M09
 72
hr
 1311 1753 5010 0.3498 0.1618
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 1
M08
 72
hr
 1311 1546 5128 0.3015 0.0871
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 2
M08
 72
hr
 1311 1455 5100 0.2853 0.0543
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 3
M08
 72
hr
 1311 1594 5010 0.3181 0.1061
MDA-MB-231 XMD16-144
10
uM
LJP5
 1
M07
 72
hr
 1311 842 5128 0.1642 -0.2018
MDA-MB-231 XMD16-144
10
uM
LJP5
 2
M07
 72
hr
 1311 670 5100 0.1314 -0.2903
MDA-MB-231 XMD16-144
10
uM
LJP5
 3
M07
 72
hr
 1311 811 5010 0.1619 -0.2202
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 1
M24
 72
hr
 1311 4950 5128 0.9652 0.9643
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 2
M24
 72
hr
 1311 4753 5100 0.9320 0.9293
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 3
M24
 72
hr
 1311 4857 5010 0.9693 0.9680
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 1
M23
 72
hr
 1311 5016 5128 0.9781 0.9776
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 2
M23
 72
hr
 1311 5025 5100 0.9853 0.9849
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 3
M23
 72
hr
 1311 4784 5010 0.9547 0.9527
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 1
M22
 72
hr
 1311 4999 5128 0.9748 0.9742
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 2
M22
 72
hr
 1311 5070 5100 0.9941 0.9940
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 3
M22
 72
hr
 1311 4987 5010 0.9952 0.9951
MDA-MB-231 Erlotinib
1.11
uM
LJP5
 1
M21
 72
hr
 1311 5081 5128 0.9908 0.9906
MDA-MB-231 Erlotinib
1.11
uM
LJP5
 2
M21
 72
hr
 1311 5101 5100 1.0002 1.0002
MDA-MB-231 Erlotinib
1.11
uM
LJP5
 3
M21
 72
hr
 1311 4861 5010 0.9701 0.9688
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 1
M20
 72
hr
 1311 5151 5128 1.0044 1.0045
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 2
M20
 72
hr
 1311 4992 5100 0.9788 0.9783
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 3
M20
 72
hr
 1311 4711 5010 0.9402 0.9372
MDA-MB-231 Erlotinib
10
uM
LJP5
 1
M19
 72
hr
 1311 3884 5128 0.7574 0.7365
MDA-MB-231 Erlotinib
10
uM
LJP5
 2
M19
 72
hr
 1311 3489 5100 0.6841 0.6477