LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Barasertib
3.33
uM
LJP5
 1
D08
 72
hr
 1311 1575 5128 0.3071 0.0975
MDA-MB-231 Barasertib
3.33
uM
LJP5
 2
D08
 72
hr
 1311 1758 5100 0.3447 0.1612
MDA-MB-231 Barasertib
3.33
uM
LJP5
 3
D08
 72
hr
 1311 1490 5010 0.2974 0.0681
MDA-MB-231 Barasertib
10
uM
LJP5
 1
D07
 72
hr
 1311 1581 5128 0.3083 0.0996
MDA-MB-231 Barasertib
10
uM
LJP5
 2
D07
 72
hr
 1311 1504 5100 0.2949 0.0723
MDA-MB-231 Barasertib
10
uM
LJP5
 3
D07
 72
hr
 1311 1438 5010 0.2870 0.0487
MDA-MB-231 Vemurafenib
0.04
uM
LJP5
 1
C18
 72
hr
 1311 4827 5128 0.9412 0.9394
MDA-MB-231 Vemurafenib
0.04
uM
LJP5
 2
C18
 72
hr
 1311 4973 5100 0.9751 0.9744
MDA-MB-231 Vemurafenib
0.04
uM
LJP5
 3
C18
 72
hr
 1311 4742 5010 0.9464 0.9438
MDA-MB-231 Vemurafenib
0.12
uM
LJP5
 1
C17
 72
hr
 1311 4799 5128 0.9358 0.9336
MDA-MB-231 Vemurafenib
0.12
uM
LJP5
 2
C17
 72
hr
 1311 4899 5100 0.9606 0.9594
MDA-MB-231 Vemurafenib
0.12
uM
LJP5
 3
C17
 72
hr
 1311 4820 5010 0.9619 0.9602
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 1
C16
 72
hr
 1311 4761 5128 0.9284 0.9258
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 2
C16
 72
hr
 1311 5260 5100 1.0314 1.0318
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 3
C16
 72
hr
 1311 4451 5010 0.8883 0.8811
MDA-MB-231 Vemurafenib
1.11
uM
LJP5
 1
C15
 72
hr
 1311 4870 5128 0.9496 0.9481
MDA-MB-231 Vemurafenib
1.11
uM
LJP5
 2
C15
 72
hr
 1311 4742 5100 0.9298 0.9271
MDA-MB-231 Vemurafenib
1.11
uM
LJP5
 3
C15
 72
hr
 1311 4583 5010 0.9146 0.9098
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 1
C14
 72
hr
 1311 4097 5128 0.7989 0.7843
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 2
C14
 72
hr
 1311 4226 5100 0.8286 0.8170
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 3
C14
 72
hr
 1311 3859 5010 0.7701 0.7473
MDA-MB-231 Vemurafenib
10
uM
LJP5
 1
C13
 72
hr
 1311 2660 5128 0.5187 0.4325
MDA-MB-231 Vemurafenib
10
uM
LJP5
 2
C13
 72
hr
 1311 2858 5100 0.5604 0.4882
MDA-MB-231 Vemurafenib
10
uM
LJP5
 3
C13
 72
hr
 1311 2715 5010 0.5418 0.4568
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
 1
D18
 72
hr
 1311 4728 5128 0.9219 0.9190