LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 1311 2562 4973 0.5151 0.4164
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 1
L10
 72
hr
 1311 2232 4870 0.4583 0.3243
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 2
L10
 72
hr
 1311 1934 4961 0.3898 0.2242
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 3
L10
 72
hr
 1311 2285 4973 0.4594 0.3346
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 1
L09
 72
hr
 1311 2048 4870 0.4205 0.2654
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 2
L09
 72
hr
 1311 1833 4961 0.3694 0.1905
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 3
L09
 72
hr
 1311 2109 4973 0.4240 0.2801
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 1311 1940 4870 0.3983 0.2297
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 1311 1800 4961 0.3628 0.1792
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 1311 1837 4973 0.3693 0.1914
MDA-MB-231 WYE-125132
10
uM
LJP6
 1
L07
 72
hr
 1311 1397 4870 0.2869 0.0338
MDA-MB-231 WYE-125132
10
uM
LJP6
 2
L07
 72
hr
 1311 1473 4961 0.2969 0.0623
MDA-MB-231 WYE-125132
10
uM
LJP6
 3
L07
 72
hr
 1311 1439 4973 0.2893 0.0493
MDA-MB-231 Barasertib
0.04
uM
LJP5
 1
D12
 72
hr
 1311 1911 5128 0.3726 0.2108
MDA-MB-231 Barasertib
0.04
uM
LJP5
 2
D12
 72
hr
 1311 1978 5100 0.3878 0.2333
MDA-MB-231 Barasertib
0.04
uM
LJP5
 3
D12
 72
hr
 1311 1936 5010 0.3864 0.2230
MDA-MB-231 Barasertib
0.12
uM
LJP5
 1
D11
 72
hr
 1311 1477 5128 0.2880 0.0622
MDA-MB-231 Barasertib
0.12
uM
LJP5
 2
D11
 72
hr
 1311 1744 5100 0.3420 0.1565
MDA-MB-231 Barasertib
0.12
uM
LJP5
 3
D11
 72
hr
 1311 1664 5010 0.3321 0.1309
MDA-MB-231 Barasertib
0.37
uM
LJP5
 1
D10
 72
hr
 1311 1628 5128 0.3175 0.1161
MDA-MB-231 Barasertib
0.37
uM
LJP5
 2
D10
 72
hr
 1311 1691 5100 0.3316 0.1384
MDA-MB-231 Barasertib
0.37
uM
LJP5
 3
D10
 72
hr
 1311 1693 5010 0.3379 0.1411
MDA-MB-231 Barasertib
1.11
uM
LJP5
 1
D09
 72
hr
 1311 1639 5128 0.3196 0.1199
MDA-MB-231 Barasertib
1.11
uM
LJP5
 2
D09
 72
hr
 1311 1719 5100 0.3371 0.1480
MDA-MB-231 Barasertib
1.11
uM
LJP5
 3
D09
 72
hr
 1311 1611 5010 0.3215 0.1121