LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | CHIR-99021 | 10 | uM | LJP6 | 2 | P13 | 72 | hr | 513 | 5001 | 10386 | 0.4815 | 0.6899 |
| MCF 10A | CHIR-99021 | 10 | uM | LJP6 | 3 | P13 | 72 | hr | 513 | 3615 | 10494 | 0.3445 | 0.5657 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 1 | J12 | 72 | hr | 513 | 11680 | 10537 | 1.1084 | 1.0478 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 2 | J12 | 72 | hr | 513 | 11790 | 10386 | 1.1351 | 1.0593 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 3 | J12 | 72 | hr | 513 | 11257 | 10494 | 1.0726 | 1.0325 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 1 | J11 | 72 | hr | 513 | 11384 | 10537 | 1.0803 | 1.0357 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 2 | J11 | 72 | hr | 513 | 11162 | 10386 | 1.0746 | 1.0335 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 3 | J11 | 72 | hr | 513 | 10792 | 10494 | 1.0283 | 1.0129 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 1 | J10 | 72 | hr | 513 | 10881 | 10537 | 1.0326 | 1.0148 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 2 | J10 | 72 | hr | 513 | 11220 | 10386 | 1.0802 | 1.0359 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 3 | J10 | 72 | hr | 513 | 10838 | 10494 | 1.0327 | 1.0148 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 1 | J09 | 72 | hr | 513 | 11021 | 10537 | 1.0458 | 1.0207 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 2 | J09 | 72 | hr | 513 | 10930 | 10386 | 1.0523 | 1.0236 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 3 | J09 | 72 | hr | 513 | 10527 | 10494 | 1.0031 | 1.0014 |
| MCF 10A | Linifanib | 3.33 | uM | LJP6 | 1 | J08 | 72 | hr | 513 | 9978 | 10537 | 0.9469 | 0.9751 |
| MCF 10A | Linifanib | 3.33 | uM | LJP6 | 2 | J08 | 72 | hr | 513 | 9765 | 10386 | 0.9401 | 0.9717 |
| MCF 10A | Linifanib | 3.33 | uM | LJP6 | 3 | J08 | 72 | hr | 513 | 9604 | 10494 | 0.9151 | 0.9597 |
| MCF 10A | Linifanib | 10 | uM | LJP6 | 1 | J07 | 72 | hr | 513 | 2860 | 10537 | 0.2714 | 0.4829 |
| MCF 10A | Linifanib | 10 | uM | LJP6 | 2 | J07 | 72 | hr | 513 | 2616 | 10386 | 0.2519 | 0.4555 |
| MCF 10A | Linifanib | 10 | uM | LJP6 | 3 | J07 | 72 | hr | 513 | 2074 | 10494 | 0.1976 | 0.3781 |
| MCF 10A | PIK-93 | 0.04 | uM | LJP5 | 1 | K18 | 72 | hr | 513 | 10064 | 10254 | 0.9814 | 0.9913 |
| MCF 10A | PIK-93 | 0.04 | uM | LJP5 | 2 | K18 | 72 | hr | 513 | 10750 | 10349 | 1.0387 | 1.0176 |
| MCF 10A | PIK-93 | 0.04 | uM | LJP5 | 3 | K18 | 72 | hr | 513 | 10117 | 10483 | 0.9650 | 0.9837 |
| MCF 10A | PIK-93 | 0.12 | uM | LJP5 | 1 | K17 | 72 | hr | 513 | 10126 | 10254 | 0.9874 | 0.9942 |
| MCF 10A | PIK-93 | 0.12 | uM | LJP5 | 2 | K17 | 72 | hr | 513 | 10887 | 10349 | 1.0519 | 1.0235 |