LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A GSK 690693
0.12
uM
LJP5
 3
F23
 72
hr
 513 9084 10483 0.8665 0.9352
MCF 10A GSK 690693
0.37
uM
LJP5
 1
F22
 72
hr
 513 8763 10254 0.8545 0.9285
MCF 10A GSK 690693
0.37
uM
LJP5
 2
F22
 72
hr
 513 9742 10349 0.9413 0.9723
MCF 10A GSK 690693
0.37
uM
LJP5
 3
F22
 72
hr
 513 8543 10483 0.8149 0.9081
MCF 10A GSK 690693
1.11
uM
LJP5
 1
F21
 72
hr
 513 6799 10254 0.6630 0.8185
MCF 10A GSK 690693
1.11
uM
LJP5
 2
F21
 72
hr
 513 7409 10349 0.7159 0.8515
MCF 10A GSK 690693
1.11
uM
LJP5
 3
F21
 72
hr
 513 7508 10483 0.7162 0.8523
MCF 10A GSK 690693
3.33
uM
LJP5
 1
F20
 72
hr
 513 6577 10254 0.6414 0.8046
MCF 10A GSK 690693
3.33
uM
LJP5
 2
F20
 72
hr
 513 7394 10349 0.7144 0.8507
MCF 10A GSK 690693
3.33
uM
LJP5
 3
F20
 72
hr
 513 7695 10483 0.7340 0.8628
MCF 10A GSK 690693
10
uM
LJP5
 1
F19
 72
hr
 513 7173 10254 0.6995 0.8412
MCF 10A GSK 690693
10
uM
LJP5
 2
F19
 72
hr
 513 7546 10349 0.7291 0.8594
MCF 10A GSK 690693
10
uM
LJP5
 3
F19
 72
hr
 513 7365 10483 0.7025 0.8442
MCF 10A SNS-032
0.04
uM
LJP6
 1
H18
 72
hr
 513 7388 10537 0.7011 0.8435
MCF 10A SNS-032
0.04
uM
LJP6
 2
H18
 72
hr
 513 6338 10386 0.6102 0.7848
MCF 10A SNS-032
0.04
uM
LJP6
 3
H18
 72
hr
 513 6947 10494 0.6620 0.8192
MCF 10A SNS-032
0.12
uM
LJP6
 1
H17
 72
hr
 513 651 10537 0.0618 0.0560
MCF 10A SNS-032
0.12
uM
LJP6
 2
H17
 72
hr
 513 556 10386 0.0535 0.0186
MCF 10A SNS-032
0.12
uM
LJP6
 3
H17
 72
hr
 513 781 10494 0.0744 0.1012
MCF 10A SNS-032
0.37
uM
LJP6
 1
H16
 72
hr
 513 583 10537 0.0553 0.0296
MCF 10A SNS-032
0.37
uM
LJP6
 2
H16
 72
hr
 513 535 10386 0.0515 0.0096
MCF 10A SNS-032
0.37
uM
LJP6
 3
H16
 72
hr
 513 530 10494 0.0505 0.0074
MCF 10A SNS-032
1.11
uM
LJP6
 1
H15
 72
hr
 513 574 10537 0.0545 0.0259
MCF 10A SNS-032
1.11
uM
LJP6
 2
H15
 72
hr
 513 399 10386 0.0384 -0.0564
MCF 10A SNS-032
1.11
uM
LJP6
 3
H15
 72
hr
 513 485 10494 0.0462 -0.0130