LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Geldanamycin
0.12
uM
LJP6
 2
O05
 72
hr
 513 540 10386 0.0520 0.0117
MCF 10A Geldanamycin
0.12
uM
LJP6
 3
O05
 72
hr
 513 567 10494 0.0540 0.0231
MCF 10A Geldanamycin
0.12
uM
LJP5
 1
O05
 72
hr
 513 445 10254 0.0434 -0.0325
MCF 10A Geldanamycin
0.12
uM
LJP5
 2
O05
 72
hr
 513 527 10349 0.0509 0.0061
MCF 10A Geldanamycin
0.12
uM
LJP5
 3
O05
 72
hr
 513 614 10483 0.0586 0.0420
MCF 10A Geldanamycin
0.37
uM
LJP6
 1
O04
 72
hr
 513 530 10537 0.0503 0.0073
MCF 10A Geldanamycin
0.37
uM
LJP6
 2
O04
 72
hr
 513 545 10386 0.0525 0.0139
MCF 10A Geldanamycin
0.37
uM
LJP6
 3
O04
 72
hr
 513 448 10494 0.0427 -0.0308
MCF 10A Geldanamycin
0.37
uM
LJP5
 1
O04
 72
hr
 513 532 10254 0.0519 0.0083
MCF 10A Geldanamycin
0.37
uM
LJP5
 2
O04
 72
hr
 513 572 10349 0.0553 0.0253
MCF 10A Geldanamycin
0.37
uM
LJP5
 3
O04
 72
hr
 513 514 10483 0.0490 0.0003
MCF 10A Geldanamycin
1.11
uM
LJP6
 1
O03
 72
hr
 513 436 10537 0.0414 -0.0368
MCF 10A Geldanamycin
1.11
uM
LJP6
 2
O03
 72
hr
 513 515 10386 0.0496 0.0007
MCF 10A Geldanamycin
1.11
uM
LJP6
 3
O03
 72
hr
 513 470 10494 0.0448 -0.0201
MCF 10A Geldanamycin
1.11
uM
LJP5
 1
O03
 72
hr
 513 420 10254 0.0410 -0.0454
MCF 10A Geldanamycin
1.11
uM
LJP5
 2
O03
 72
hr
 513 597 10349 0.0577 0.0354
MCF 10A Geldanamycin
1.11
uM
LJP5
 3
O03
 72
hr
 513 467 10483 0.0445 -0.0215
MCF 10A Geldanamycin
3.33
uM
LJP6
 1
O02
 72
hr
 513 366 10537 0.0347 -0.0747
MCF 10A Geldanamycin
3.33
uM
LJP6
 2
O02
 72
hr
 513 375 10386 0.0361 -0.0698
MCF 10A Geldanamycin
3.33
uM
LJP6
 3
O02
 72
hr
 513 438 10494 0.0417 -0.0358
MCF 10A Geldanamycin
3.33
uM
LJP5
 1
O02
 72
hr
 513 400 10254 0.0390 -0.0561
MCF 10A Geldanamycin
3.33
uM
LJP5
 2
O02
 72
hr
 513 329 10349 0.0318 -0.0976
MCF 10A Geldanamycin
3.33
uM
LJP5
 3
O02
 72
hr
 513 439 10483 0.0419 -0.0353
MCF 10A Geldanamycin
10
uM
LJP6
 1
O01
 72
hr
 513 280 10537 0.0266 -0.1298
MCF 10A Geldanamycin
10
uM
LJP6
 2
O01
 72
hr
 513 223 10386 0.0215 -0.1748