LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Geldanamycin
10
uM
LJP6
 3
O01
 72
hr
 513 283 10494 0.0270 -0.1279
MCF 10A Geldanamycin
10
uM
LJP5
 1
O01
 72
hr
 513 315 10254 0.0307 -0.1069
MCF 10A Geldanamycin
10
uM
LJP5
 2
O01
 72
hr
 513 335 10349 0.0324 -0.0938
MCF 10A Geldanamycin
10
uM
LJP5
 3
O01
 72
hr
 513 273 10483 0.0260 -0.1351
MCF 10A YM 201636
0.04
uM
LJP5
 1
N12
 72
hr
 513 10636 10254 1.0372 1.0170
MCF 10A YM 201636
0.04
uM
LJP5
 2
N12
 72
hr
 513 11238 10349 1.0858 1.0384
MCF 10A YM 201636
0.04
uM
LJP5
 3
N12
 72
hr
 513 10448 10483 0.9966 0.9984
MCF 10A YM 201636
0.12
uM
LJP5
 1
N11
 72
hr
 513 9696 10254 0.9455 0.9742
MCF 10A YM 201636
0.12
uM
LJP5
 2
N11
 72
hr
 513 10725 10349 1.0363 1.0165
MCF 10A YM 201636
0.12
uM
LJP5
 3
N11
 72
hr
 513 9193 10483 0.8769 0.9405
MCF 10A YM 201636
0.37
uM
LJP5
 1
N10
 72
hr
 513 8891 10254 0.8670 0.9350
MCF 10A YM 201636
0.37
uM
LJP5
 2
N10
 72
hr
 513 9478 10349 0.9158 0.9598
MCF 10A YM 201636
0.37
uM
LJP5
 3
N10
 72
hr
 513 8594 10483 0.8198 0.9107
MCF 10A YM 201636
1.11
uM
LJP5
 1
N09
 72
hr
 513 5929 10254 0.5782 0.7618
MCF 10A YM 201636
1.11
uM
LJP5
 2
N09
 72
hr
 513 7021 10349 0.6784 0.8287
MCF 10A YM 201636
1.11
uM
LJP5
 3
N09
 72
hr
 513 6549 10483 0.6247 0.7951
MCF 10A YM 201636
3.33
uM
LJP5
 1
N08
 72
hr
 513 4795 10254 0.4676 0.6773
MCF 10A YM 201636
3.33
uM
LJP5
 2
N08
 72
hr
 513 5879 10349 0.5680 0.7553
MCF 10A YM 201636
3.33
uM
LJP5
 3
N08
 72
hr
 513 4915 10483 0.4688 0.6805
MCF 10A YM 201636
10
uM
LJP5
 1
N07
 72
hr
 513 1304 10254 0.1272 0.2408
MCF 10A YM 201636
10
uM
LJP5
 2
N07
 72
hr
 513 1526 10349 0.1475 0.2858
MCF 10A YM 201636
10
uM
LJP5
 3
N07
 72
hr
 513 1338 10483 0.1276 0.2462
MCF 10A TWS119
0.04
uM
LJP5
 1
M06
 72
hr
 513 11042 10254 1.0768 1.0345
MCF 10A TWS119
0.04
uM
LJP5
 2
M06
 72
hr
 513 11259 10349 1.0879 1.0393
MCF 10A TWS119
0.04
uM
LJP5
 3
M06
 72
hr
 513 10376 10483 0.9897 0.9953