LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Torin1
10
uM
LJP6
 2
O13
 72
hr
 513 987 10386 0.0950 0.1626
MCF 10A Torin1
10
uM
LJP6
 3
O13
 72
hr
 513 607 10494 0.0578 0.0392
MCF 10A Torin2
0.04
uM
LJP5
 1
I24
 72
hr
 513 1059 10254 0.1033 0.1825
MCF 10A Torin2
0.04
uM
LJP5
 2
I24
 72
hr
 513 583 10349 0.0563 0.0298
MCF 10A Torin2
0.04
uM
LJP5
 3
I24
 72
hr
 513 813 10483 0.0776 0.1114
MCF 10A Torin2
0.12
uM
LJP5
 1
I23
 72
hr
 513 440 10254 0.0429 -0.0351
MCF 10A Torin2
0.12
uM
LJP5
 2
I23
 72
hr
 513 515 10349 0.0498 0.0007
MCF 10A Torin2
0.12
uM
LJP5
 3
I23
 72
hr
 513 561 10483 0.0535 0.0206
MCF 10A Torin2
0.37
uM
LJP5
 1
I22
 72
hr
 513 397 10254 0.0387 -0.0578
MCF 10A Torin2
0.37
uM
LJP5
 2
I22
 72
hr
 513 494 10349 0.0477 -0.0088
MCF 10A Torin2
0.37
uM
LJP5
 3
I22
 72
hr
 513 525 10483 0.0501 0.0052
MCF 10A Torin2
1.11
uM
LJP5
 1
I21
 72
hr
 513 390 10254 0.0380 -0.0616
MCF 10A Torin2
1.11
uM
LJP5
 2
I21
 72
hr
 513 539 10349 0.0521 0.0113
MCF 10A Torin2
1.11
uM
LJP5
 3
I21
 72
hr
 513 523 10483 0.0499 0.0043
MCF 10A Torin2
3.33
uM
LJP5
 1
I20
 72
hr
 513 527 10254 0.0514 0.0061
MCF 10A Torin2
3.33
uM
LJP5
 2
I20
 72
hr
 513 449 10349 0.0434 -0.0304
MCF 10A Torin2
3.33
uM
LJP5
 3
I20
 72
hr
 513 611 10483 0.0583 0.0408
MCF 10A Torin2
10
uM
LJP5
 1
I19
 72
hr
 513 470 10254 0.0458 -0.0202
MCF 10A Torin2
10
uM
LJP5
 2
I19
 72
hr
 513 478 10349 0.0462 -0.0163
MCF 10A Torin2
10
uM
LJP5
 3
I19
 72
hr
 513 504 10483 0.0481 -0.0042
MCF 10A WZ-4-145
0.04
uM
LJP6
 1
J24
 72
hr
 513 8853 10537 0.8401 0.9217
MCF 10A WZ-4-145
0.04
uM
LJP6
 2
J24
 72
hr
 513 8923 10386 0.8591 0.9312
MCF 10A WZ-4-145
0.04
uM
LJP6
 3
J24
 72
hr
 513 8719 10494 0.8308 0.9166
MCF 10A WZ-4-145
0.12
uM
LJP6
 1
J23
 72
hr
 513 8829 10537 0.8378 0.9205
MCF 10A WZ-4-145
0.12
uM
LJP6
 2
J23
 72
hr
 513 9219 10386 0.8876 0.9458