LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Brivanib | 3.33 | uM | LJP5 | 2 | P14 | 72 | hr | 1476 | 3087 | 3731 | 0.8273 | 0.7357 |
| SK-BR-3 | Brivanib | 3.33 | uM | LJP5 | 3 | P14 | 72 | hr | 1476 | 3210 | 3796 | 0.8455 | 0.7682 |
| SK-BR-3 | Brivanib | 10 | uM | LJP5 | 1 | P13 | 72 | hr | 1476 | 3364 | 3788 | 0.8879 | 0.8325 |
| SK-BR-3 | Brivanib | 10 | uM | LJP5 | 2 | P13 | 72 | hr | 1476 | 3054 | 3731 | 0.8185 | 0.7218 |
| SK-BR-3 | Brivanib | 10 | uM | LJP5 | 3 | P13 | 72 | hr | 1476 | 2983 | 3796 | 0.7857 | 0.6755 |
| SK-BR-3 | CHIR-99021 | 0.04 | uM | LJP6 | 1 | P18 | 72 | hr | 1476 | 3012 | 3413 | 0.8824 | 0.8034 |
| SK-BR-3 | CHIR-99021 | 0.04 | uM | LJP6 | 2 | P18 | 72 | hr | 1476 | 2770 | 3783 | 0.7321 | 0.5895 |
| SK-BR-3 | CHIR-99021 | 0.04 | uM | LJP6 | 3 | P18 | 72 | hr | 1476 | 2747 | 3734 | 0.7357 | 0.5901 |
| SK-BR-3 | CHIR-99021 | 0.12 | uM | LJP6 | 1 | P17 | 72 | hr | 1476 | 2979 | 3413 | 0.8728 | 0.7870 |
| SK-BR-3 | CHIR-99021 | 0.12 | uM | LJP6 | 2 | P17 | 72 | hr | 1476 | 2757 | 3783 | 0.7287 | 0.5840 |
| SK-BR-3 | CHIR-99021 | 0.12 | uM | LJP6 | 3 | P17 | 72 | hr | 1476 | 2688 | 3734 | 0.7199 | 0.5645 |
| SK-BR-3 | CHIR-99021 | 0.37 | uM | LJP6 | 1 | P16 | 72 | hr | 1476 | 2821 | 3413 | 0.8265 | 0.7083 |
| SK-BR-3 | CHIR-99021 | 0.37 | uM | LJP6 | 2 | P16 | 72 | hr | 1476 | 3060 | 3783 | 0.8088 | 0.7105 |
| SK-BR-3 | CHIR-99021 | 0.37 | uM | LJP6 | 3 | P16 | 72 | hr | 1476 | 2956 | 3734 | 0.7916 | 0.6796 |
| SK-BR-3 | CHIR-99021 | 1.11 | uM | LJP6 | 1 | P15 | 72 | hr | 1476 | 3009 | 3413 | 0.8816 | 0.8019 |
| SK-BR-3 | CHIR-99021 | 1.11 | uM | LJP6 | 2 | P15 | 72 | hr | 1476 | 2925 | 3783 | 0.7731 | 0.6546 |
| SK-BR-3 | CHIR-99021 | 1.11 | uM | LJP6 | 3 | P15 | 72 | hr | 1476 | 2749 | 3734 | 0.7362 | 0.5909 |
| SK-BR-3 | CHIR-99021 | 3.33 | uM | LJP6 | 1 | P14 | 72 | hr | 1476 | 2722 | 3413 | 0.7975 | 0.6585 |
| SK-BR-3 | CHIR-99021 | 3.33 | uM | LJP6 | 2 | P14 | 72 | hr | 1476 | 2969 | 3783 | 0.7847 | 0.6729 |
| SK-BR-3 | CHIR-99021 | 3.33 | uM | LJP6 | 3 | P14 | 72 | hr | 1476 | 2912 | 3734 | 0.7799 | 0.6609 |
| SK-BR-3 | CHIR-99021 | 10 | uM | LJP6 | 1 | P13 | 72 | hr | 1476 | 2425 | 3413 | 0.7105 | 0.5073 |
| SK-BR-3 | CHIR-99021 | 10 | uM | LJP6 | 2 | P13 | 72 | hr | 1476 | 2246 | 3783 | 0.5936 | 0.3620 |
| SK-BR-3 | CHIR-99021 | 10 | uM | LJP6 | 3 | P13 | 72 | hr | 1476 | 2066 | 3734 | 0.5533 | 0.2852 |
| SK-BR-3 | Linifanib | 0.04 | uM | LJP6 | 1 | J12 | 72 | hr | 1476 | 3579 | 3413 | 1.0485 | 1.0800 |
| SK-BR-3 | Linifanib | 0.04 | uM | LJP6 | 2 | J12 | 72 | hr | 1476 | 4207 | 3783 | 1.1119 | 1.1626 |