LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Trametinib | 10 | uM | LJP5 | 1 | P19 | 72 | hr | 1476 | 2581 | 3788 | 0.6813 | 0.5080 |
| SK-BR-3 | Trametinib | 10 | uM | LJP5 | 2 | P19 | 72 | hr | 1476 | 2609 | 3731 | 0.6992 | 0.5305 |
| SK-BR-3 | Trametinib | 10 | uM | LJP5 | 3 | P19 | 72 | hr | 1476 | 2491 | 3796 | 0.6561 | 0.4679 |
| SK-BR-3 | Omipalisib | 0.04 | uM | LJP6 | 1 | N06 | 72 | hr | 1476 | 1389 | 3413 | 0.4069 | -0.0494 |
| SK-BR-3 | Omipalisib | 0.04 | uM | LJP6 | 2 | N06 | 72 | hr | 1476 | 1752 | 3783 | 0.4631 | 0.1342 |
| SK-BR-3 | Omipalisib | 0.04 | uM | LJP6 | 3 | N06 | 72 | hr | 1476 | 1483 | 3734 | 0.3972 | 0.0032 |
| SK-BR-3 | Omipalisib | 0.12 | uM | LJP6 | 1 | N05 | 72 | hr | 1476 | 1321 | 3413 | 0.3870 | -0.0881 |
| SK-BR-3 | Omipalisib | 0.12 | uM | LJP6 | 2 | N05 | 72 | hr | 1476 | 1511 | 3783 | 0.3994 | 0.0171 |
| SK-BR-3 | Omipalisib | 0.12 | uM | LJP6 | 3 | N05 | 72 | hr | 1476 | 1444 | 3734 | 0.3867 | -0.0166 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 1 | N04 | 72 | hr | 1476 | 1256 | 3413 | 0.3680 | -0.1254 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 2 | N04 | 72 | hr | 1476 | 1331 | 3783 | 0.3518 | -0.0737 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 3 | N04 | 72 | hr | 1476 | 1303 | 3734 | 0.3490 | -0.0893 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 1 | N03 | 72 | hr | 1476 | 1057 | 3413 | 0.3097 | -0.2417 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 2 | N03 | 72 | hr | 1476 | 1394 | 3783 | 0.3684 | -0.0416 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 3 | N03 | 72 | hr | 1476 | 1380 | 3734 | 0.3696 | -0.0494 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 1 | N02 | 72 | hr | 1476 | 856 | 3413 | 0.2508 | -0.3631 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 2 | N02 | 72 | hr | 1476 | 1136 | 3783 | 0.3003 | -0.1757 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 3 | N02 | 72 | hr | 1476 | 1153 | 3734 | 0.3088 | -0.1688 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 1 | N01 | 72 | hr | 1476 | 702 | 3413 | 0.2057 | -0.4595 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 2 | N01 | 72 | hr | 1476 | 733 | 3783 | 0.1937 | -0.4031 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 3 | N01 | 72 | hr | 1476 | 862 | 3734 | 0.2309 | -0.3312 |
| SK-BR-3 | Buparlisib | 0.04 | uM | LJP5 | 1 | H06 | 72 | hr | 1476 | 3865 | 3788 | 1.0202 | 1.0296 |
| SK-BR-3 | Buparlisib | 0.04 | uM | LJP5 | 2 | H06 | 72 | hr | 1476 | 3583 | 3731 | 0.9603 | 0.9403 |
| SK-BR-3 | Buparlisib | 0.04 | uM | LJP5 | 3 | H06 | 72 | hr | 1476 | 3778 | 3796 | 0.9951 | 0.9928 |
| SK-BR-3 | Buparlisib | 0.12 | uM | LJP5 | 1 | H05 | 72 | hr | 1476 | 3019 | 3788 | 0.7969 | 0.6923 |