LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Buparlisib | 0.12 | uM | LJP5 | 2 | H05 | 72 | hr | 1476 | 3024 | 3731 | 0.8105 | 0.7092 |
| SK-BR-3 | Buparlisib | 0.12 | uM | LJP5 | 3 | H05 | 72 | hr | 1476 | 3128 | 3796 | 0.8239 | 0.7349 |
| SK-BR-3 | Buparlisib | 0.37 | uM | LJP5 | 1 | H04 | 72 | hr | 1476 | 1766 | 3788 | 0.4661 | 0.1407 |
| SK-BR-3 | Buparlisib | 0.37 | uM | LJP5 | 2 | H04 | 72 | hr | 1476 | 1585 | 3731 | 0.4248 | 0.0543 |
| SK-BR-3 | Buparlisib | 0.37 | uM | LJP5 | 3 | H04 | 72 | hr | 1476 | 1683 | 3796 | 0.4433 | 0.1007 |
| SK-BR-3 | Buparlisib | 1.11 | uM | LJP5 | 1 | H03 | 72 | hr | 1476 | 1097 | 3788 | 0.2896 | -0.1964 |
| SK-BR-3 | Buparlisib | 1.11 | uM | LJP5 | 2 | H03 | 72 | hr | 1476 | 1158 | 3731 | 0.3104 | -0.1662 |
| SK-BR-3 | Buparlisib | 1.11 | uM | LJP5 | 3 | H03 | 72 | hr | 1476 | 1168 | 3796 | 0.3076 | -0.1582 |
| SK-BR-3 | Buparlisib | 3.33 | uM | LJP5 | 1 | H02 | 72 | hr | 1476 | 1108 | 3788 | 0.2925 | -0.1905 |
| SK-BR-3 | Buparlisib | 3.33 | uM | LJP5 | 2 | H02 | 72 | hr | 1476 | 967 | 3731 | 0.2592 | -0.2714 |
| SK-BR-3 | Buparlisib | 3.33 | uM | LJP5 | 3 | H02 | 72 | hr | 1476 | 1018 | 3796 | 0.2681 | -0.2389 |
| SK-BR-3 | Buparlisib | 10 | uM | LJP5 | 1 | H01 | 72 | hr | 1476 | 848 | 3788 | 0.2238 | -0.3351 |
| SK-BR-3 | Buparlisib | 10 | uM | LJP5 | 2 | H01 | 72 | hr | 1476 | 816 | 3731 | 0.2187 | -0.3583 |
| SK-BR-3 | Buparlisib | 10 | uM | LJP5 | 3 | H01 | 72 | hr | 1476 | 906 | 3796 | 0.2386 | -0.3014 |
| SK-BR-3 | XL147 | 0.04 | uM | LJP5 | 1 | G12 | 72 | hr | 1476 | 3992 | 3788 | 1.0537 | 1.0784 |
| SK-BR-3 | XL147 | 0.04 | uM | LJP5 | 2 | G12 | 72 | hr | 1476 | 4302 | 3731 | 1.1530 | 1.2246 |
| SK-BR-3 | XL147 | 0.04 | uM | LJP5 | 3 | G12 | 72 | hr | 1476 | 4398 | 3796 | 1.1584 | 1.2279 |
| SK-BR-3 | XL147 | 0.12 | uM | LJP5 | 1 | G11 | 72 | hr | 1476 | 4465 | 3788 | 1.1785 | 1.2569 |
| SK-BR-3 | XL147 | 0.12 | uM | LJP5 | 2 | G11 | 72 | hr | 1476 | 4128 | 3731 | 1.1063 | 1.1570 |
| SK-BR-3 | XL147 | 0.12 | uM | LJP5 | 3 | G11 | 72 | hr | 1476 | 4347 | 3796 | 1.1450 | 1.2089 |
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 1 | G10 | 72 | hr | 1476 | 4585 | 3788 | 1.2102 | 1.3014 |
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 2 | G10 | 72 | hr | 1476 | 4241 | 3731 | 1.1366 | 1.2010 |
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 3 | G10 | 72 | hr | 1476 | 4027 | 3796 | 1.0607 | 1.0884 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 1 | G09 | 72 | hr | 1476 | 4824 | 3788 | 1.2733 | 1.3890 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 2 | G09 | 72 | hr | 1476 | 4091 | 3731 | 1.0964 | 1.1425 |