LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 1 | N01 | 72 | hr | 1476 | 702 | 3413 | 0.2057 | -0.4595 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 3 | C19 | 72 | hr | 1476 | 640 | 3796 | 0.1686 | -0.4587 |
| BT-20 | LDN-193189 | 10 | uM | LJP5 | 2 | G01 | 72 | hr | 1657 | 566 | 5610 | 0.1009 | -0.4572 |
| Hs 578T | Withaferin A | 10 | uM | LJP6 | 1 | G13 | 72 | hr | 929 | 315 | 3185 | 0.0989 | -0.4559 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 1235 | 446 | 3974 | 0.1122 | -0.4536 |
| SK-BR-3 | AZD7762 | 10 | uM | LJP6 | 1 | L01 | 72 | hr | 1476 | 712 | 3413 | 0.2086 | -0.4531 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 1235 | 434 | 4126 | 0.1052 | -0.4519 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP6 | 3 | O01 | 72 | hr | 1476 | 664 | 3734 | 0.1778 | -0.4497 |
| MCF7 | SNS-032 | 0.12 | uM | LJP6 | 1 | H17 | 72 | hr | 1235 | 456 | 3974 | 0.1147 | -0.4464 |
| MCF7 | AZD 5438 | 10 | uM | LJP6 | 3 | J01 | 72 | hr | 1235 | 444 | 4126 | 0.1076 | -0.4446 |
| MCF7 | CGP60474 | 3.33 | uM | LJP6 | 3 | G02 | 72 | hr | 1235 | 449 | 4126 | 0.1088 | -0.4411 |
| BT-20 | LDN-193189 | 10 | uM | LJP5 | 3 | G01 | 72 | hr | 1657 | 608 | 5529 | 0.1100 | -0.4385 |
| MCF7 | Canertinib | 10 | uM | LJP6 | 3 | H07 | 72 | hr | 1235 | 454 | 4126 | 0.1100 | -0.4375 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 1 | C19 | 72 | hr | 1235 | 455 | 4119 | 0.1105 | -0.4372 |
| BT-20 | CGP60474 | 10 | uM | LJP6 | 2 | G01 | 72 | hr | 1657 | 629 | 5360 | 0.1174 | -0.4358 |
| SK-BR-3 | CGP60474 | 10 | uM | LJP5 | 1 | F01 | 72 | hr | 1476 | 686 | 3788 | 0.1811 | -0.4311 |
| MCF7 | Geldanamycin | 10 | uM | LJP6 | 1 | O01 | 72 | hr | 1235 | 479 | 3974 | 0.1205 | -0.4300 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 868 | 276 | 3587 | 0.0769 | -0.4287 |
| SK-BR-3 | HG-6-64-01 | 10 | uM | LJP6 | 3 | M01 | 72 | hr | 1476 | 698 | 3734 | 0.1869 | -0.4287 |
| SK-BR-3 | AT-7519 | 10 | uM | LJP6 | 2 | K01 | 72 | hr | 1476 | 691 | 3783 | 0.1826 | -0.4285 |
| MCF7 | SNS-032 | 1.11 | uM | LJP6 | 2 | H15 | 72 | hr | 1235 | 472 | 4070 | 0.1160 | -0.4284 |
| SK-BR-3 | AT-7519 | 10 | uM | LJP6 | 3 | K01 | 72 | hr | 1476 | 699 | 3734 | 0.1872 | -0.4281 |
| SK-BR-3 | LDN-193189 | 10 | uM | LJP5 | 3 | G01 | 72 | hr | 1476 | 692 | 3796 | 0.1823 | -0.4267 |
| MCF7 | A443654 | 3.33 | uM | LJP6 | 3 | I20 | 72 | hr | 1235 | 470 | 4126 | 0.1139 | -0.4262 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 868 | 289 | 3429 | 0.0843 | -0.4259 |