LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Nintedanib | 0.04 | uM | LJP6 | 2 | H06 | 72 | hr | 1235 | 3536 | 4070 | 0.8687 | 0.8429 |
| MCF7 | Nintedanib | 0.04 | uM | LJP6 | 3 | H06 | 72 | hr | 1235 | 4129 | 4126 | 1.0006 | 1.0007 |
| MCF7 | Nintedanib | 0.12 | uM | LJP6 | 1 | H05 | 72 | hr | 1235 | 3230 | 3974 | 0.8128 | 0.7685 |
| MCF7 | Nintedanib | 0.12 | uM | LJP6 | 2 | H05 | 72 | hr | 1235 | 3688 | 4070 | 0.9061 | 0.8885 |
| MCF7 | Nintedanib | 0.12 | uM | LJP6 | 3 | H05 | 72 | hr | 1235 | 3645 | 4126 | 0.8834 | 0.8624 |
| MCF7 | Nintedanib | 0.37 | uM | LJP6 | 1 | H04 | 72 | hr | 1235 | 2977 | 3974 | 0.7491 | 0.6850 |
| MCF7 | Nintedanib | 0.37 | uM | LJP6 | 2 | H04 | 72 | hr | 1235 | 2577 | 4070 | 0.6331 | 0.5333 |
| MCF7 | Nintedanib | 0.37 | uM | LJP6 | 3 | H04 | 72 | hr | 1235 | 2823 | 4126 | 0.6841 | 0.6080 |
| MCF7 | Nintedanib | 1.11 | uM | LJP6 | 1 | H03 | 72 | hr | 1235 | 2225 | 3974 | 0.5599 | 0.4177 |
| MCF7 | Nintedanib | 1.11 | uM | LJP6 | 2 | H03 | 72 | hr | 1235 | 2000 | 4070 | 0.4914 | 0.3232 |
| MCF7 | Nintedanib | 1.11 | uM | LJP6 | 3 | H03 | 72 | hr | 1235 | 2134 | 4126 | 0.5172 | 0.3691 |
| MCF7 | Nintedanib | 3.33 | uM | LJP6 | 1 | H02 | 72 | hr | 1235 | 1308 | 3974 | 0.3291 | 0.0345 |
| MCF7 | Nintedanib | 3.33 | uM | LJP6 | 2 | H02 | 72 | hr | 1235 | 1480 | 4070 | 0.3636 | 0.1107 |
| MCF7 | Nintedanib | 3.33 | uM | LJP6 | 3 | H02 | 72 | hr | 1235 | 1602 | 4126 | 0.3882 | 0.1611 |
| MCF7 | Nintedanib | 10 | uM | LJP6 | 1 | H01 | 72 | hr | 1235 | 768 | 3974 | 0.1933 | -0.2457 |
| MCF7 | Nintedanib | 10 | uM | LJP6 | 2 | H01 | 72 | hr | 1235 | 822 | 4070 | 0.2020 | -0.2109 |
| MCF7 | Nintedanib | 10 | uM | LJP6 | 3 | H01 | 72 | hr | 1235 | 943 | 4126 | 0.2285 | -0.1438 |
| MCF7 | Foretinib | 0.04 | uM | LJP5 | 1 | H12 | 72 | hr | 1235 | 3940 | 4119 | 0.9565 | 0.9495 |
| MCF7 | Foretinib | 0.04 | uM | LJP5 | 2 | H12 | 72 | hr | 1235 | 4240 | 4356 | 0.9733 | 0.9705 |
| MCF7 | Foretinib | 0.04 | uM | LJP5 | 3 | H12 | 72 | hr | 1235 | 4477 | 4326 | 1.0348 | 1.0382 |
| MCF7 | Foretinib | 0.12 | uM | LJP5 | 1 | H11 | 72 | hr | 1235 | 1765 | 4119 | 0.4285 | 0.2280 |
| MCF7 | Foretinib | 0.12 | uM | LJP5 | 2 | H11 | 72 | hr | 1235 | 1950 | 4356 | 0.4476 | 0.2854 |
| MCF7 | Foretinib | 0.12 | uM | LJP5 | 3 | H11 | 72 | hr | 1235 | 1904 | 4326 | 0.4401 | 0.2703 |
| MCF7 | Foretinib | 0.37 | uM | LJP5 | 1 | H10 | 72 | hr | 1235 | 1428 | 4119 | 0.3467 | 0.0870 |
| MCF7 | Foretinib | 0.37 | uM | LJP5 | 2 | H10 | 72 | hr | 1235 | 1665 | 4356 | 0.3822 | 0.1784 |