LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | XL147 | 3.33 | uM | LJP5 | 1 | G08 | 72 | hr | 1235 | 4508 | 4119 | 1.0944 | 1.1066 |
| MCF7 | XL147 | 3.33 | uM | LJP5 | 2 | G08 | 72 | hr | 1235 | 4515 | 4356 | 1.0364 | 1.0398 |
| MCF7 | XL147 | 3.33 | uM | LJP5 | 3 | G08 | 72 | hr | 1235 | 5078 | 4326 | 1.1737 | 1.1852 |
| MCF7 | XL147 | 10 | uM | LJP5 | 1 | G07 | 72 | hr | 1235 | 2775 | 4119 | 0.6737 | 0.5933 |
| MCF7 | XL147 | 10 | uM | LJP5 | 2 | G07 | 72 | hr | 1235 | 2521 | 4356 | 0.5787 | 0.4804 |
| MCF7 | XL147 | 10 | uM | LJP5 | 3 | G07 | 72 | hr | 1235 | 2775 | 4326 | 0.6414 | 0.5645 |
| MCF7 | Y39983 | 0.04 | uM | LJP6 | 1 | P06 | 72 | hr | 1235 | 4477 | 3974 | 1.1265 | 1.1465 |
| MCF7 | Y39983 | 0.04 | uM | LJP6 | 2 | P06 | 72 | hr | 1235 | 4097 | 4070 | 1.0065 | 1.0076 |
| MCF7 | Y39983 | 0.04 | uM | LJP6 | 3 | P06 | 72 | hr | 1235 | 4173 | 4126 | 1.0113 | 1.0130 |
| MCF7 | Y39983 | 0.12 | uM | LJP6 | 1 | P05 | 72 | hr | 1235 | 4185 | 3974 | 1.0531 | 1.0623 |
| MCF7 | Y39983 | 0.12 | uM | LJP6 | 2 | P05 | 72 | hr | 1235 | 4028 | 4070 | 0.9896 | 0.9879 |
| MCF7 | Y39983 | 0.12 | uM | LJP6 | 3 | P05 | 72 | hr | 1235 | 4333 | 4126 | 1.0501 | 1.0570 |
| MCF7 | Y39983 | 0.37 | uM | LJP6 | 1 | P04 | 72 | hr | 1235 | 4075 | 3974 | 1.0254 | 1.0300 |
| MCF7 | Y39983 | 0.37 | uM | LJP6 | 2 | P04 | 72 | hr | 1235 | 3954 | 4070 | 0.9714 | 0.9666 |
| MCF7 | Y39983 | 0.37 | uM | LJP6 | 3 | P04 | 72 | hr | 1235 | 4005 | 4126 | 0.9706 | 0.9660 |
| MCF7 | Y39983 | 1.11 | uM | LJP6 | 1 | P03 | 72 | hr | 1235 | 3396 | 3974 | 0.8545 | 0.8219 |
| MCF7 | Y39983 | 1.11 | uM | LJP6 | 2 | P03 | 72 | hr | 1235 | 3353 | 4070 | 0.8238 | 0.7868 |
| MCF7 | Y39983 | 1.11 | uM | LJP6 | 3 | P03 | 72 | hr | 1235 | 3267 | 4126 | 0.7917 | 0.7488 |
| MCF7 | Y39983 | 3.33 | uM | LJP6 | 1 | P02 | 72 | hr | 1235 | 2254 | 3974 | 0.5672 | 0.4286 |
| MCF7 | Y39983 | 3.33 | uM | LJP6 | 2 | P02 | 72 | hr | 1235 | 2295 | 4070 | 0.5638 | 0.4334 |
| MCF7 | Y39983 | 3.33 | uM | LJP6 | 3 | P02 | 72 | hr | 1235 | 2204 | 4126 | 0.5341 | 0.3948 |
| MCF7 | Y39983 | 10 | uM | LJP6 | 1 | P01 | 72 | hr | 1235 | 547 | 3974 | 0.1376 | -0.3833 |
| MCF7 | Y39983 | 10 | uM | LJP6 | 2 | P01 | 72 | hr | 1235 | 697 | 4070 | 0.1712 | -0.2830 |
| MCF7 | Y39983 | 10 | uM | LJP6 | 3 | P01 | 72 | hr | 1235 | 622 | 4126 | 0.1507 | -0.3259 |
| MCF7 | Nintedanib | 0.04 | uM | LJP6 | 1 | H06 | 72 | hr | 1235 | 4332 | 3974 | 1.0900 | 1.1050 |