LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Dovitinib
0.12
uM
LJP5
 1
E23
 72
hr
 1235 3198 4119 0.7764 0.7288
MCF7 Dovitinib
0.12
uM
LJP5
 2
E23
 72
hr
 1235 3339 4356 0.7665 0.7278
MCF7 Dovitinib
0.12
uM
LJP5
 3
E23
 72
hr
 1235 3786 4326 0.8751 0.8577
MCF7 Dovitinib
0.37
uM
LJP5
 1
E22
 72
hr
 1235 2861 4119 0.6946 0.6215
MCF7 Dovitinib
0.37
uM
LJP5
 2
E22
 72
hr
 1235 3076 4356 0.7061 0.6516
MCF7 Dovitinib
0.37
uM
LJP5
 3
E22
 72
hr
 1235 3093 4326 0.7149 0.6612
MCF7 Dovitinib
1.11
uM
LJP5
 1
E21
 72
hr
 1235 2822 4119 0.6851 0.6088
MCF7 Dovitinib
1.11
uM
LJP5
 2
E21
 72
hr
 1235 2759 4356 0.6333 0.5557
MCF7 Dovitinib
1.11
uM
LJP5
 3
E21
 72
hr
 1235 2967 4326 0.6858 0.6234
MCF7 Dovitinib
3.33
uM
LJP5
 1
E20
 72
hr
 1235 2166 4119 0.5258 0.3815
MCF7 Dovitinib
3.33
uM
LJP5
 2
E20
 72
hr
 1235 2232 4356 0.5124 0.3845
MCF7 Dovitinib
3.33
uM
LJP5
 3
E20
 72
hr
 1235 2247 4326 0.5194 0.3921
MCF7 Dovitinib
10
uM
LJP5
 1
E19
 72
hr
 1235 2211 4119 0.5368 0.3980
MCF7 Dovitinib
10
uM
LJP5
 2
E19
 72
hr
 1235 2210 4356 0.5073 0.3770
MCF7 Dovitinib
10
uM
LJP5
 3
E19
 72
hr
 1235 2170 4326 0.5016 0.3655
MCF7 GSK 690693
0.04
uM
LJP5
 1
F24
 72
hr
 1235 2317 4119 0.5625 0.4362
MCF7 GSK 690693
0.04
uM
LJP5
 2
F24
 72
hr
 1235 2747 4356 0.6306 0.5520
MCF7 GSK 690693
0.04
uM
LJP5
 3
F24
 72
hr
 1235 2901 4326 0.6705 0.6034
MCF7 GSK 690693
0.12
uM
LJP5
 1
F23
 72
hr
 1235 2085 4119 0.5062 0.3515
MCF7 GSK 690693
0.12
uM
LJP5
 2
F23
 72
hr
 1235 2103 4356 0.4828 0.3399
MCF7 GSK 690693
0.12
uM
LJP5
 3
F23
 72
hr
 1235 2451 4326 0.5665 0.4607
MCF7 GSK 690693
0.37
uM
LJP5
 1
F22
 72
hr
 1235 2023 4119 0.4911 0.3283
MCF7 GSK 690693
0.37
uM
LJP5
 2
F22
 72
hr
 1235 2115 4356 0.4855 0.3441
MCF7 GSK 690693
0.37
uM
LJP5
 3
F22
 72
hr
 1235 2368 4326 0.5473 0.4331
MCF7 GSK 690693
1.11
uM
LJP5
 1
F21
 72
hr
 1235 1932 4119 0.4690 0.2935